Evidence map›Paper›PMID 38337478›Full record

ArticleJournal of clinical medicine2024

Analgesic Efficacy of Oxycodone in Postoperative Dressings after Surgical Treatment of Burn Wounds: A Randomised Controlled Trial.

Grzegorz Kowalski, Wojciech Leppert, Małgorzata Domagalska, Monika Grochowicka, Artur Teżyk, Krzysztof Słowiński, Agnieszka Bienert, Danuta Szkutnik-Fiedler, Katarzyna Wieczorowska-Tobis

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Oxycodone versus sufentanil on pain management for spinal PVP surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Peptide-Based Approaches for Pain Relief and Healing in Wounds.International journal of molecular sciences · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Grzegorz KowalskiDepartment of Palliative Medicine, Poznan University of Medical Sciences, 61-701 Pozan, Poland.
Wojciech LeppertDepartment of Palliative Medicine, Institute of Medical Sciences Collegium Medicum, University of Zielona Góra, 65-046 Zielona Góra, Poland.ORCID 0000-0003-0852-2535
Małgorzata DomagalskaDepartment of Palliative Medicine, Poznan University of Medical Sciences, 61-701 Pozan, Poland.ORCID 0000-0002-9067-0969
Monika GrochowickaDepartment of Palliative Medicine, Poznan University of Medical Sciences, 61-701 Pozan, Poland.
Artur TeżykDepartment of Forensic Medicine, Poznan University of Medical Sciences, 61-701 Poznań, Poland.
Krzysztof SłowińskiDepartment of Trauma, Burns and Plastic Surgery, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Agnieszka BienertChair and Department of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, 61-701 Poznań, Poland.
Danuta Szkutnik-FiedlerChair and Department of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, 61-701 Poznań, Poland.ORCID 0000-0002-1856-1733
Katarzyna Wieczorowska-TobisDepartment of Palliative Medicine, Poznan University of Medical Sciences, 61-701 Pozan, Poland.
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to assess the analgesic efficacy of oxycodone at doses of 10 mg and 20 mg in dressings after surgery of burn wounds. MATERIAL AND

methodsTwenty adult patients who underwent surgical treatment of third-degree burn wounds under general anaesthesia were included. Burn wounds were treated with dressings, to which oxycodone was added at 20 mg in Group 1 and 10 mg in Group 2. After the surgery, plasma oxycodone and noroxycodone concentrations were assayed, and pain intensity was assessed with Numerical Rating Scale (NRS).

resultsIn Group 1, no patient reported pain; in Group 2, four patients reported pain. The pain intensity, according to NRS, was 1-8. Plasma concentration of oxycodone in the blood serum was in the range of 1.24-3.15 ng/mL and 1.09-1.28 ng/mL in Group 1 and Group 2, respectively. Noroxycodone was not detected in the plasma. Adverse effects were not observed in any of the treated patients.

conclusionsOxycodone in dressings provides patients with adequate and safe analgesia.

Indexed as

burnsfentanylmorphineopioidsoxycodonepainwounds

Identifiers

PMID38337478
PMCPMC10856020
OpenAlexW4391345018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.