ArticleJournal of clinical medicine2024
A Data-Driven Framework for Clinical Decision Support Systems in Positive Airway Pressure and Oxygen Titration.
Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundCurrent obstructive sleep apnea treatment relies on manual PAP titration, but it has limitations. Complex interactions during titration and variations in SpO
methodsThis study, compliant with data protection laws, focused on adults with OSA-induced hypoxemia utilizing supplemental oxygen and CPAP/BiPAP therapy. PAP titration, conducted over one night, involved vigilant monitoring of vital signs and physiological parameters. Adjustments to CPAP pressure, potential BiLevel transitions, and supplemental oxygen were precisely guided by patient metrics. Markov decision processes outlined three treatment actions for disorder management, incorporating expert medical insights.
resultsIn our study involving 14 OSA patients (average age: 63 years, 27% females, BMI 41 kg m
conclusionsThe development of a framework for Markov decision processes of PAP and oxygen titration algorithms holds promise for providing algorithms for improving pCO
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