ReviewJournal of clinical medicine2024
Personalized Multimodal Lifestyle Intervention as the Best-Evidenced Treatment for Chronic Pain: State-of-the-Art Clinical Perspective.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What do we know about flares in spinal and pelvic girdle pain? A scoping review.BMC musculoskeletal disorders · 2026Pooled it
- Probiotics and palmitoylethanolamide (PEA) for osteoarthritic pain: individual effects in a multiple baseline design study.BMC complementary medicine and therapies · 2026Trial
- Canadian Adaptation of REVEAL(OT) for Chronic Pain Management: Rapid Qualitative Analysis Results.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2026Article
- Potential therapeutic targets for multisite chronic pain: A proteome-wide Mendelian randomization study.Medicine · 2026Article
- Implementation status and barriers to multimodal management of low back pain among physical therapists: A cross-sectional study.Scientific reports · 2026Article
- What is the Evidence on Lifestyle Interventions for the Symptom Management of Pelvic Pain in Women With Endometriosis or Adenomyosis? A Scoping Review.American journal of lifestyle medicine · 2026Review
- Impact of nutritional profile on pain and functionality in patients with frozen shoulder: a cross-sectional observational study.Frontiers in medicine · 2026Article
- Rethinking Pain Assessment: Subjective Scales, Biomarkers, and Multimodal Integration.Journal of pain research · 2026Review
- Toward Precision Acupuncture for Pain: Host Genetic Variability, Omics Biomarkers, and Treatment-Response Stratification.Human mutation · 2026Review
- Exploring the associations of cortical connectivity-modulation with clinical and psychological measures in acute low back pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Article
- Perspectives on Pain: A Narrative Review of Pain Beliefs, Coping, and Clinical Implications.Journal of pain research · 2026Review
- Oral and Gut Health, (Neuro) Inflammation, and Central Sensitization in Chronic Pain: A Narrative Review of Mechanisms, Treatment Opportunities, and Research Agenda.International journal of molecular sciences · 2025Review
- In the Mouth or in the Gut? Innovation Through Implementing Oral and Gastrointestinal Health Science in Chronic Pain Management.Journal of clinical medicine · 2025Article
- Virtual reality in chronic pain management: how do we galvanize a stagnant field?Pain management · 2025Article
- Nutrition care in pain rehabilitation-success and lessons from practice.Pain management · 2025Review
- Dolodoc, an App to Leverage Self-Management of Chronic Pain: Design, Development, and Implementation Report.JMIR medical informatics · 2025Article
- Frequencies of persistence, activity pacing, fear avoidance and general stress in acute neck pain.Comprehensive psychoneuroendocrinology · 2025Review
- Harnessing Extended Reality for Neurocognitive Training in Chronic Pain: State of the Art, Opportunities, and Future Directions.Healthcare (Basel, Switzerland) · 2025Review
- Microalgae and exercise: from molecular mechanisms and brain health to clinical perspectives in the context of 3P medicine.The EPMA journal · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic pain is the most prevalent disease worldwide, leading to substantial disability and socioeconomic burden. Therefore, it can be regarded as a public health disease and major challenge to scientists, clinicians and affected individuals. Behavioral lifestyle factors, such as, physical (in)activity, stress, poor sleep and an unhealthy diet are increasingly recognized as perpetuating factors for chronic pain. Yet, current management options for patients with chronic pain often do not address lifestyle factors in a personalized multimodal fashion. This state-of-the-art clinical perspective aims to address this gap by discussing how clinicians can simultaneously incorporate various lifestyle factors into a personalized multimodal lifestyle intervention for individuals with chronic pain. To do so the available evidence on (multimodal) lifestyle interventions targeting physical (in)activity, stress, sleep and nutritional factors, specifically, was reviewed and synthetized from a clinical point of view. First, advise is provided on how to design a personalized multimodal lifestyle approach for a specific patient. Subsequently, best-evidence recommendations on how to integrate physical (in)activity, stress, sleep and nutritional factors as treatment targets into a personalized multimodal lifestyle approach are outlined. Evidence supporting such a personalized multimodal lifestyle approach is growing, but further studies are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.