Evidence map›Paper›PMID 38337193›Full record

ArticleBrain and behavior2024

UK Medical Cannabis Registry: Assessment of clinical outcomes in patients with insomnia.

Kavyesh Vivek, Zekiye Karagozlu, Simon Erridge, Carl Holvey, Ross Coomber, James J Rucker, Mark W Weatherall, Mikael H Sodergren

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Health-related quality of life in patients receiving medicinal cannabis: systematic review and meta-analysis of primary research findings 2015-2025.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kavyesh VivekImperial College Medical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.ORCID 0000-0003-1815-6460
Zekiye KaragozluImperial College Medical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.
Simon ErridgeImperial College Medical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.ORCID 0000-0001-5871-6501
Carl HolveyDepartment of Medicine, Curaleaf Clinic, London, UK.
Ross CoomberDepartment of Medicine, Curaleaf Clinic, London, UK.
James J RuckerDepartment of Medicine, Curaleaf Clinic, London, UK.
Mark W WeatherallDepartment of Medicine, Curaleaf Clinic, London, UK.
Mikael H SodergrenImperial College Medical Cannabis Research Group, Department of Surgery and Cancer, Imperial College London, London, UK.
London Clinic · GBImperial College London · GBKing's College London · GBSt George's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe primary aim of this study was to assess changes in sleep-specific health-related quality of life (HRQoL) for those prescribed cannabis-based medicinal products (CBMPs) for insomnia.

methodsA case series of UK patients with insomnia was analyzed. Primary outcomes were changes in the Single-Item Sleep-Quality Scale (SQS), Generalized Anxiety Disorder-7 (GAD-7), and EQ-5D-5L at up to 6 months from baseline. Statistical significance was identified as a p value < .050.

results61 patients were included in the analysis. There was an improvement in the SQS from baseline at 1, 3, and 6 months (p < .001). There were also improvements in the EQ-5D-5L Index value and GAD-7 at 1, 3, and 6 months (p < .050). There were 28 (45.9%) adverse events recorded by 8 patients (13.1%). There were no life-threatening/disabling adverse events.

conclusionPatients with insomnia experienced an improvement in sleep quality following the initiation of CBMPs in this medium-term analysis. Fewer than 15% of participants reported one or more adverse events. However, due to the limitations of the study design, further investigation is required before definitive conclusions can be drawn on the efficacy of CBMPs in treating insomnia.

Indexed as

CannabisMedical MarijuanaSleep Initiation and Maintenance DisordersHumansQuality of LifeRegistriesUnited KingdomMedical Marijuanabenzodiazepinescannabis-based medicinal productsinsomniasleep quality

Identifiers

PMID38337193
PMCPMC10858318
OpenAlexW4391722473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.