Evidence map›Paper›PMID 38336915›Full record

ArticleScientific reports2024

An artificial intelligence based abdominal aortic aneurysm prognosis classifier to predict patient outcomes.

Timothy K Chung, Pete H Gueldner, Okechukwu U Aloziem, Nathan L Liang, David A Vorp

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

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  18. Thoracic Aortic Shape: A Data-Driven Scale Space Approach.medRxiv : the preprint server for health sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Timothy K ChungDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Pete H GueldnerDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Okechukwu U AloziemSchool of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Nathan L LiangDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
David A VorpDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA. vorp@pitt.edu.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

A Machine Learning-Based Clinical Decision Support Tool to Predict Abdominal Aortic Aneurysm Prognosis Using Existing Longitudinal DataR21HL156246 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VORP, DAVID ALAN · 2021 to 2022
$236k
NHLBI NIH HHS R21 HL156246NIH HHS HL156246
6 · The paper itself

Abstract

Abdominal aortic aneurysms (AAA) have been rigorously investigated to understand when their clinically-estimated risk of rupture-an event that is the 13th leading cause of death in the US-exceeds the risk associated with repair. Yet the current clinical guideline remains a one-size-fits-all "maximum diameter criterion" whereby AAA exceeding a threshold diameter is thought to make the risk of rupture high enough to warrant intervention. However, between 7 and 23.4% of smaller-sized AAA have been reported to rupture with diameters below the threshold. In this study, we train and assess machine learning models using clinical, biomechanical, and morphological indices from 381 patients to develop an aneurysm prognosis classifier to predict one of three outcomes for a given AAA patient: their AAA will remain stable, their AAA will require repair based as currently indicated from the maximum diameter criterion, or their AAA will rupture. This study represents the largest cohort of AAA patients that utilizes the first available medical image and clinical data to classify patient outcomes. The APC model therefore represents a potential clinical tool to striate specific patient outcomes using machine learning models and patient-specific image-based (biomechanical and morphological) and clinical data as input. Such a tool could greatly assist clinicians in their management decisions for patients with AAA.

Indexed as

Aortic Aneurysm, AbdominalArtificial IntelligenceHumansMachine LearningPrognosisRisk Factors

Identifiers

PMID38336915
PMCPMC10858046
OpenAlexW4391677331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.