Evidence map›Paper›PMID 38336900›Full record

ReviewPlant cell reports2024

TALE-based organellar genome editing and gene expression in plants.

Jer-Young Lin, Yu-Chang Liu, Yan-Hao Tseng, Ming-Tsair Chan, Ching-Chun Chang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jer-Young LinAgricultural Biotechnology Research Center, Academia Sinica, Tainan, 71150, Taiwan.
Yu-Chang LiuAgricultural Biotechnology Research Center, Academia Sinica, Tainan, 71150, Taiwan.
Yan-Hao TsengDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, 70101, Taiwan.
Ming-Tsair ChanAgricultural Biotechnology Research Center, Academia Sinica, Tainan, 71150, Taiwan. mbmtchan@gate.sinica.edu.tw.ORCID http://orcid.org/0000-0002-1942-9160
Ching-Chun ChangDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, 70101, Taiwan. chingcc@mail.ncku.edu.tw.ORCID http://orcid.org/0000-0003-1002-1756
Agricultural Biotechnology Research Center, Academia Sinica · TWNational Cheng Kung University · TW

Funding

National Science and Technology Council NSTC 112-2313-B-006-004
6 · The paper itself

Abstract

key messageTALE-based editors provide an alternative way to engineer the organellar genomes in plants. We update and discuss the most recent developments of TALE-based organellar genome editing in plants. Gene editing tools have been widely used to modify the nuclear genomes of plants for various basic research and biotechnological applications. The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 editing platform is the most commonly used technique because of its ease of use, fast speed, and low cost; however, it encounters difficulty when being delivered to plant organelles for gene editing. In contrast, protein-based editing technologies, such as transcription activator-like effector (TALE)-based tools, could be easily delivered, expressed, and targeted to organelles in plants via Agrobacteria-mediated nuclear transformation. Therefore, TALE-based editors provide an alternative way to engineer the organellar genomes in plants since the conventional chloroplast transformation method encounters technical challenges and is limited to certain species, and the direct transformation of mitochondria in higher plants is not yet possible. In this review, we update and discuss the most recent developments of TALE-based organellar genome editing in plants.

Indexed as

Gene EditingTranscription Activator-Like EffectorsCRISPR-Cas SystemsGene ExpressionGenome, PlantOrganellesPlantsTranscription Activator-Like EffectorsChloroplastGene editingMitochondriaOrganellar genome editingTALE

Identifiers

PMID38336900
OpenAlexW4391826588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.