Evidence map›Paper›PMID 38336732›Full record

ArticleBMC urology2024

Prostate cancer presentation and management in the Middle East.

Mutlay Sayan, Astrid Langoe, Ozlem Aynaci, Ayfer Ay Eren, Mehmet Fuat Eren, Ilke Onur Kazaz, Zainab Ibrahim, Omar Tama Al-Akelie, Loma Al-Mansouri, Ramiz Abu-Hijlih and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 7 countries.

Mutlay SayanBrigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. msayan@bwh.harvard.edu.
Astrid LangoeBoston College, Boston, MA, USA.
Ozlem AynaciKaradeniz Technical University, Trabzon, Türkiye, Turkey.
Ayfer Ay ErenKartal Dr. Lütfi Kirdar Education and Research Hospital, Istanbul, Turkey.
Mehmet Fuat ErenMarmara University, Istanbul Pendik Education and Research Hospital, Istanbul, Türkiye, Turkey.
Ilke Onur KazazKaradeniz Technical University, Trabzon, Türkiye, Turkey.
Zainab IbrahimKing Hamad University Hospital, Al Sayh, Bahrain.
Omar Tama Al-AkelieAlamal National Hospital for Cancer Management, Baghdad, Iraq.
Loma Al-MansouriBasrah Medical College, Basra, Iraq.
Ramiz Abu-HijlihKing Hussein Cancer Center, Amman, Jordan.
Shalini MoningiBrigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Elia Abou ChawarebAmerican University of Beirut Medical Center, Beirut, Lebanon.
Albert El HajjAmerican University of Beirut Medical Center, Beirut, Lebanon.
Peter F OrioBrigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Layth Mula-HussainFaculty of Medicine, Dalhousie University, Halifax, NS, Canada.
American University of Beirut Medical Center · LBBrigham and Women's Hospital · USKaradeniz Technical University · TRBaghdad Medical City · IQBoston College · USDana-Farber Brigham Cancer Center · USDr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi · TRKing Hamad University Hospital · BHKing Hussein Cancer Center · JOMarmara University · TRUniversity of Basrah · IQUniversity of Mosul · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough prostate cancer is a prevalent malignancy worldwide, its clinical presentation and management in the Middle East are not well-documented. This study aims to provide insights into the initial clinical presentation and management of prostate cancer in this region.

methodsA retrospective review was conducted on seven institutional databases from six Middle Eastern countries, including Türkiye, Lebanon, Iraq, Syria, Bahrain, and Jordan, to identify patients diagnosed with prostate cancer in 2021. Descriptive analysis was performed on the collected data to provide an overview of the demographic, clinical, and treatment variables.

resultsA total of 1,136 patients were identified with a median age of 70 (range, 50-84). Most patients (78%) received their prostate cancer diagnosis after presenting with symptoms, as opposed to routine PSA screening. At the time of diagnosis, 35% of men had clinical T3 or T4 disease, 54% with Stage IV disease and 50% with Gleason score ≥ 8. Regarding treatment, 20% of non-metastatic and 22% of metastatic patients received no treatment.

conclusionMost men in this study sought prostate cancer evaluation due to symptoms and were subsequently diagnosed with advanced-stage disease, providing a foundation for future research aimed at understanding the underlying factors behind the observed trends and enabling informed interventions.

Indexed as

Prostate-Specific AntigenProstatic NeoplasmsHumansIraqLebanonMaleNeoplasm StagingRetrospective StudiesProstate-Specific AntigenDiagnostic challengesDisease managementDisease presentationMiddle EastProstatic neoplasms

Identifiers

PMID38336732
PMCPMC10858578
OpenAlexW4391679063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.