ArticleBMC public health2024
Allostatic load and chronic pain: a prospective finding from the national survey of midlife development in the United States, 2004-2014.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07746284 (Network Modeling in Knee Osteoarthritis), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Network Modeling in Knee Osteoarthritis
Who cites it
11 citing papers in PubMed.
- Investigating associations between allostatic load phenotypes and clinical impairment in youth with chronic pain.Brain, behavior, & immunity - health · 2026Article
- Association between allostatic load and incident dementia, and race/ethnic disparities in the association in the U.S. health and retirement study.Psychoneuroendocrinology · 2026Article
- Unmet health-related social needs are associated with pain outcomes among midlife and older adults.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Allostatic load profiles, resilience, and psychosocial adaptation in young adults.Frontiers in psychology · 2026Article
- The expectations we build: reframing chronic pain outcomes as a systems level public health issue.Frontiers in public health · 2026Article
- Intersecting race/ethnicity and gender in physiological dysregulation profiles and associations with socioeconomic status among older adults in the United States.SSM - population health · 2025Article
- Reaching Veterans with Cooccurring Mental Health Conditions Through the VA Whole Health System of Care.Journal of integrative and complementary medicine · 2025Article
- Capturing Patients' Lived Experiences with Chronic Pain through Motivational Interviewing and Information Extraction.Proceedings of the ... Workshop on Patient-Oriented Language Processing · 2025Article
- Neighborhood disadvantage and pain-related experiences in a pain psychology clinic: The mediating roles of pain catastrophizing and pain-related fear.The journal of pain · 2025Article
- Rethinking chronic pain: a dissociative framework for psychodynamic practice.Frontiers in psychology · 2025Review
- The relationship between neonatal stress in preterm infants and developmental outcomes at the corrected age of 24-30 months.Frontiers in psychology · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
Abstract
backgroundPrevious research has demonstrated a correlation between chronic stress and chronic pain (CP). However, there have been few studies examining the prospective association of allostatic load (AL)-the biological processes related to stress-with CP.
methodsWe firstly conducted latent class analysis to identify phenotypes of AL using a community-dwelling sample, the Midlife in the United States. Multinomial logistic regression models were used to examine the prospective association between phenotypes of AL at MIDUS 2 biomarker project and the presence of CP, CP interference and the number of CP sites at MIDUS 3.
resultsThree phenotypes of AL, low biological dysregulation, parasympathetic dysregulation and metabolic dysregulation, were identified. Compared to low biological dysregulation group, participants experiencing metabolic dysregulation phenotype of AL at MIDUS 2 had higher risks of having high-interference CP (RRR = 2.00, 95% CI: 1.06, 3.79, P < 0.05) and 3 or more CP sites (RRR = 2.03, 95% CI: 1.08, 3.83, P < 0.05) at MIDUS 3.
conclusionThe findings indicate that focusing on mitigating the metabolic dysfunction phenotype of AL has the potential to be an efficacious strategy for alleviating future CP bodily widespreadness and high CP interference.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.