Evidence map›Paper›PMID 38336646›Full record

ArticleBMC immunology2024

Hyperactivation and enhanced cytotoxicity of reduced CD8

Tao Zhu, Linlin Zhu, Caixia Sheng, Danju Wu, Qianru Gu, Zhinong Jiang, Jiaqi Xu, Guoxiang Fu, Yujie Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tao Zhu *Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Linlin Zhu *Department of Gastroenterology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Caixia ShengDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Danju WuDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Qianru GuDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Zhinong JiangDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Jiaqi XuDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Guoxiang FuDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Yujie JiangDepartment of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China. yujie17@zju.edu.cn.
Sir Run Run Shaw Hospital · CNZhejiang University · CN

Funding

National Natural Science Foundation of China 81800459
6 · The paper itself

Abstract

BACKGROUND AND

aimsWe aimed to investigate the immune characteristics of intestinal CD8

methodsThe study cohorts included 21 CD patients and 21 healthy individuals. CD8

resultsThe study revealed a reduction in intestinal CD8

conclusionsIntestinal CD8

Indexed as

Crohn DiseaseIntraepithelial LymphocytesGranzymesHLA-DR AntigensHumansIntestinal MucosaPerforinReceptors, Antigen, T-Cell, gamma-deltaT-Lymphocytes, CytotoxicGranzymesHLA-DR AntigensPerforinReceptors, Antigen, T-Cell, gamma-deltaCD8+ gamma delta T cellCrohn’s diseaseDisease activityImmune characteristics

Identifiers

PMID38336646
PMCPMC10858568
OpenAlexW4391692187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.