ArticleBMC anesthesiology2024
The value of pupillary diameter in evaluating pain perception after awakening in patients undergoing general anesthesia during orthopedic surgery.
Article in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 2 citations in OpenAlex.
- Prevention of Intraoperative Acquired Pressure Injury in Patients With Head and Neck Cancer and Its Effect on Skin Microclimate: A Single-Blind Randomised Controlled Trial.International wound journal · 2025Trial
- Comparison of clinical effectiveness between interlaminar and transforaminal endoscopic lumbar discectomy for L4/5 highly migrated lumbar disc herniation: a retrospective study with a minimum one year follow-up.BMC musculoskeletal disorders · 2026Article
- Preoperative pupillary metrics as predictors of postoperative acute and chronic pain following thoracoscopic surgery: a prospective study.American journal of translational research · 2025Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe pupillary response to tetanic electrical stimulation reflects the balance between nociceptive stimulation and analgesia. Although pupillary pain index (PPI) was utilized to predict postoperative pain, it depended on tetanic stimulation and was complex. We aim to describe the potential relationship between PD in the presence of surgical stimulation and pain levels after awakening.
methodsAccording to the Verbal Rating Scale (VRS) score after extubation, the patients were divided into painless group (VRS = 0) and pain group (VRS ≥ 1). Pupillary diameter (PD) and pupillary light reflex velocity (PLRV) were compared between two groups when patients entered the operating room (T
resultsPatients with VRS ≥ 1 had greater PD than painless patients at T
conclusionOur study indicates that PD is a useful index to direct the individualized analgesics used during operation, to better avoid the occurrence of pain during the postoperative emergence period.
trial registrationThis study was registered with the Chinese Clinical Trial Registry (registration number: ChiCTR2000040908, registration date: 15/12/2020).
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