Evidence map›Paper›PMID 38334934›Full record

ArticleDigestive diseases and sciences2024

Restoration of the Mucosal IgA Response by Improving CD4

Zi-Meng Liu, Yi-Nan Zhang, Hu-Fei Zhang, Xiao-Jun Chen, Hui Peng, Xu-Yu Zhang

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zi-Meng Liu *Department of Critical Care Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Yi-Nan Zhang *Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510089, China.
Hu-Fei Zhang *Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510089, China.
Xiao-Jun ChenDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510089, China.
Hui PengDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510089, China.
Xu-Yu ZhangDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510089, China. zhangxuy@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-0637-3049
Sun Yat-sen University · CN

Funding

Natural Science Foundation of Guangdong Province 2021A1515010990
6 · The paper itself

Abstract

backgroundCurrently, the mechanisms of impaired gut mucosal immunity in sepsis remain unclear. Gut immunoglobulin A (IgA) is an important defense mechanism against invasive pathogens, and CD4

aimWe aimed to verify the hypothesis indicating that CD4

methodsCultured CD4

resultsLPS attack induced CD4

conclusionLPS attack results in CD4

Indexed as

Immunoglobulin ALipopolysaccharidesAnimalsBacterial TranslocationCD4-Positive T-LymphocytesMicePyroptosisImmunoglobulin ALipopolysaccharidesCD4+ TGutIgA responseMucosal immunityPyroptosisSepsis

Identifiers

PMID38334934
OpenAlexW4391684025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.