Evidence map›Paper›PMID 38334886›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2024

Inner Ear Organoids: Strengths and Limitations.

Giulia Pianigiani, Marta Roccio

Abstract read
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Inner Ear Organoids: Recent Progress and Challenges.Stem cell reviews and reports · 2026
    Review
  2. Review
  3. Recent Progress in Mechanism-Based Therapies forInternational journal of molecular sciences · 2026
    Review
  4. Stem cell-based and gene editing strategies in the treatment of congenital and acquired sensorineural hearing loss: a narrative review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  5. Neural Hearing Loss: Mechanisms, Diagnosis and Treatment Horizons.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
  6. Review
  7. Review
  8. The rise of cochlear gene therapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  9. Article
  10. Pharmacological Approaches to Hearing Loss.Pharmacological reviews · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giulia PianigianiInstitute for Maternal and Child Health - I.R.C.C.S. "Burlo Garofolo", Trieste, Italy.ORCID http://orcid.org/0000-0003-0851-1473
Marta RoccioInner Ear Stem Cell Lab, Department Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich and University of Zurich, USZ Campus WAGI18, Wagistrasse 18, 8952, Schlieren, Switzerland. Marta.roccio@usz.ch.ORCID http://orcid.org/0000-0001-7568-9429

Funding

Congressionally Directed Medical Research Programs W81xWH211810Novartis Stiftung für Medizinisch-Biologische Forschung 22B133
6 · The paper itself

Abstract

Inner ear organoids derived from differentiation of human pluripotent stem cells have recently gained momentum as tools to study inner ear development and developmental defects. An additional exciting aspect about this technology is represented by its translational potential, specifically, the use of organoids to validate therapeutics for hearing and balance restoration on human/patient-specific cells. This latter aspect will be briefly discussed here including opportunities and current limitations.

Indexed as

Ear, InnerCell DifferentiationHearingHumansOrganoidsHearing lossHuman iPSC-derived organoidsInner ear biology

Identifiers

PMID38334886
PMCPMC10907556

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.