Evidence map›Paper›PMID 38334675›Full record

ArticleCells2024

Human β-Defensin 3 Inhibition of

Erika Inoue, Shiyo Minatozaki, Sachi Shimizu, Sayaka Miyamoto, Misato Jo, Junjun Ni, Hidetoshi Tozaki-Saitoh, Kosuke Oda, Saori Nonaka, Hiroshi Nakanishi

Open access · goldAbstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Candidalysin InhibitsInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Noradrenaline Synergistically EnhancesInternational journal of molecular sciences · 2025
    Article
  8. Alzheimer's Disease andLife (Basel, Switzerland) · 2025
    Review
  9. Outer membrane vesicles ofFrontiers in microbiology · 2025
    Review
  10. Review
  11. Oral Pathobiont-Derived Outer Membrane Vesicles in the Oral-Gut Axis.International journal of molecular sciences · 2024
    Review
  12. Frontiers in cellular and infection microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Erika InoueFaculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Shiyo MinatozakiFaculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Sachi ShimizuFaculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Sayaka MiyamotoFaculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Misato JoFaculty of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan.
Junjun NiKey Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Hidetoshi Tozaki-SaitohDepartment of Pharmaceutical Sciences, School of Pharmacy at Fukuoka, International University of Health and Welfare, Okawa 831-8501, Japan.ORCID 0000-0003-0423-2143
Kosuke OdaDepartment of Pharmacology, Faculty of Pharmacy, Yasuda Women's University, Yasuhigashi, Hiroshima 731-0153, Japan.ORCID 0000-0002-1095-548X
Saori NonakaDepartment of Pharmacology, Faculty of Pharmacy, Yasuda Women's University, Yasuhigashi, Hiroshima 731-0153, Japan.
Hiroshi NakanishiDepartment of Pharmacology, Faculty of Pharmacy, Yasuda Women's University, Yasuhigashi, Hiroshima 731-0153, Japan.ORCID 0000-0003-2610-3203
Yasuda Women's University · JPBeijing Institute of Technology · CNFukuoka International University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cathepsin B (CatB) is thought to be essential for the induction of

Indexed as

beta-DefensinsMicrogliaCathepsin BHumansI-kappa B KinaseInflammasomesInterleukin-1betaLipopolysaccharidesNF-kappa BNF-KappaB Inhibitor alphaNLR Family, Pyrin Domain-Containing 3 ProteinVirulence Factorsbeta-DefensinsCathepsin BI-kappa B KinaseInflammasomesInterleukin-1betaLipopolysaccharidesNF-kappa BNF-KappaB Inhibitor alphaNLR Family, Pyrin Domain-Containing 3 ProteinVirulence FactorsBV-2 microgliaCA-074Mecathepsin Bhuman β-defensin 3interleukin-1βlipopolysaccharidenuclear factor-κBouter membrane vesiclesPorphyromonas gingivalis

Identifiers

PMID38334675
PMCPMC10854704
OpenAlexW4391531712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.