Evidence map›Paper›PMID 38334626›Full record

ArticleCells2024

Investigation into Cardiac Myhc-α 334-352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity.

Meghna Sur, Mahima T Rasquinha, Kiruthiga Mone, Chandirasegaran Massilamany, Ninaad Lasrado, Channabasavaiah Gurumurthy, Raymond A Sobel, Jay Reddy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Meghna SurSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-0878-4930
Mahima T RasquinhaSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-0923-4869
Kiruthiga MoneSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-0379-4152
Chandirasegaran MassilamanySchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Ninaad LasradoSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0001-6762-2654
Channabasavaiah GurumurthyDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Raymond A SobelDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-0477-9002
Jay ReddySchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-4082-9254
University of Nebraska–Lincoln · USStanford University · USUniversity of Nebraska Medical Center · US

Funding

TCR Transgenic Models for Dilated CardiomyopathyR21AI142281 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI REDDY, JAY · 2019 to 2020
$403k
NIAID NIH HHS R21 AI142281NIH HHS 5R21AI142281-02
6 · The paper itself

Abstract

Myocarditis is one of the major causes of heart failure in children and young adults and can lead to dilated cardiomyopathy. Lymphocytic myocarditis could result from autoreactive CD4

Indexed as

AutoimmunityMyocarditisAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansMiceMice, Inbred C57BLMice, TransgenicMyosin Heavy ChainsReceptors, Antigen, T-CellT-Lymphocytes, CytotoxicMyh6 protein, mouseMyosin Heavy ChainsReceptors, Antigen, T-Cellcardiac myosin-α 334–352inflammatory cardiomyopathymyocarditisTCR transgenic mice

Identifiers

PMID38334626
PMCPMC10854502
OpenAlexW4391262674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.