ArticleRadiology. Imaging cancer2024
Breast Cancer Detection Using a Low-Dose Positron Emission Digital Mammography System.
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Article in Radiology. Imaging cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Patterns of positron emission mammography uptake by benign and malignant breast lesions: radiopathological correlation with malignant histopathological subtypes, histological grades, and molecular subtypes.Annals of nuclear medicine · 2026Article
- Deep unrolled regularization for limited-angle dual-panel positron emission mammography.Physical and engineering sciences in medicine · 2026Article
- Modelling image quality over extended [Frontiers in oncology · 2026Article
- Multi-angle acquisition and 3D composite reconstruction for organ-targeted PET using planar detectors.Medical physics · 2025Article
- Radiotracer Innovations in Breast Cancer Imaging: A Review of Recent Progress.Diagnostics (Basel, Switzerland) · 2024Review
- Low-Dose Positron Emission Mammography: A Novel, Promising Technique for Breast Cancer Detection.Radiology. Imaging cancer · 2024Article
- Case report: Possible role of low-dose PEM for avoiding unneeded procedures associated with false-positive or equivocal breast MRI results.Frontiers in oncology · 2024Article
- Image quality evaluation for a clinical organ-targeted PET camera.Frontiers in oncology · 2024Article
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Vivianne FreitasFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).ORCID 0000-0003-2563-0861
Xuan LiFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Anabel ScaraneloFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).ORCID 0000-0002-0326-412X
Frederick AuFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).ORCID 0000-0002-2610-5084
Supriya KulkarniFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).ORCID 0000-0002-5120-9248
Sandeep GhaiFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).ORCID 0000-0001-9626-9941
Samira TaebFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Oleksandr BubonFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Brandon BaldassiFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Borys KomarovFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Shayna ParkerFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Craig A MacsemchukFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Michael WaterstonFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).ORCID 0009-0007-1634-5520
Kenneth O OlsenFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
Alla ReznikFrom the Temerty Faculty of Medicine, Joint Department of Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9 (V.F., A.S., F.A., S.K., S.G.); Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada (X.L.); Thunder Bay Regional Health Research Institute, Thunder Bay, Canada (S.T., O.B., A.R.); Lakehead University, Thunder Bay, Canada (O.B., B.B., A.R.); Radialis Inc, Thunder Bay, Canada (O.B., B.B., B.K., S.P., C.A.M., M.W., K.O.O.); Institute of Biomedical Engineering, University of Toronto, Toronto, Canada (C.A.M.); and Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, Toronto, Canada (C.A.M.).
University Health Network · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose To investigate the feasibility of low-dose positron emission mammography (PEM) concurrently to MRI to identify breast cancer and determine its local extent. Materials and Methods In this research ethics board-approved prospective study, participants newly diagnosed with breast cancer with concurrent breast MRI acquisitions were assigned independently of breast density, tumor size, and histopathologic cancer subtype to undergo low-dose PEM with up to 185 MBq of fluorine 18-labeled fluorodeoxyglucose (
Indexed as
Breast NeoplasmsElectronsFemaleFluorodeoxyglucose F18HumansMammographyMiddle AgedPositron-Emission TomographyProspective StudiesRadiopharmaceuticalsTomography, X-Ray ComputedFluorodeoxyglucose F18RadiopharmaceuticalsInvasive Breast CancerMRIOncologyPositron Emission Digital Mammography
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