Evidence map›Paper›PMID 38334090›Full record

ReviewPharmaceutical biology2024

Comparative efficacy and safety of Chinese medicine injections as an adjunctive therapy for cervical cancer in Chinese patients: a network meta-analysis.

Fei Ma, Qun Wang, Di Zhang, Zihong Wang, Hui Xie, Xianghong Liu, Hongxing Zhang, Haiyan Song, Shiguang Sun

Open access · goldAbstract readReviewNetwork Meta-Analysis
In one paragraph

Review in Pharmaceutical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fei MaOffice of Party Committee (Director), Affiliated Hospital, Shandong Provincial Hospital of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
Qun WangCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
Di ZhangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Zihong WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Hui XieCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Xianghong LiuDepartment of Pharmacy, Qilu Hospital, Shandong University, Jinan, China.
Hongxing ZhangDepartment of Pharmacy, Jinan Hospital of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
Haiyan SongDepartment of Pharmacy, Second Affiliated Hospital, Shandong Provincial Hospital of Integrated Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
Shiguang SunCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Shandong University of Traditional Chinese Medicine · CNShandong Provincial Hospital · CNHanzhong People's Hospital · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextChinese medicine injections (CMIs) are widely used as adjuvant therapy for cervical cancer in China. However, the effectiveness of different types of CMIs remains uncertain.

objectiveTo assess the effectiveness and safety of CMIs when used in conjunction with radiotherapy (RT) or concurrent chemoradiotherapy (CCRT), particularly in combination with cisplatin (DDP), docetaxel plus cisplatin (DP), and paclitaxel plus cisplatin (TP). MATERIALS AND

methodsRandomized controlled trials (RCTs) were searched in databases including CNKI, WanFang, VIP, SinoMed, PubMed, Cochrane Library, Embase, and Web of Science from inception to September 2023. We calculated the risk ratio with a 95% confidence interval and the surface under the cumulative ranking area curve (SUCRA) for the clinical efficacy rate (CER), the efficacy rate by Karnofsky Performance Status (KPS), and the rates of leukopenia reduction (LRR) and gastrointestinal reactions (GRR).

resultsForty-seven RCTs were included, including nine CMI types:

conclusionsThe optimal recommendation depends on whether CMIs are used with radiotherapy or concurrent chemoradiotherapy. More high-quality RCTs are needed to confirm further and update the existing evidence.

Indexed as

Drugs, Chinese HerbalUterine Cervical NeoplasmsCisplatinCombined Modality TherapyFemaleHumansMedicine, Chinese TraditionalCisplatinDrugs, Chinese HerbalChinese medicine injections (CMIs)concurrent chemoradiotherapy (CCRT)efficacynetwork meta-analysisRadiotherapy (RT)randomized controlled trials (RCTs)safety

Identifiers

PMID38334090
PMCPMC10860435
OpenAlexW4391680170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.