Evidence map›Paper›PMID 38333899›Full record

ReviewDrug design, development and therapy2024

Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan.

Bradley S Miller, Jo Blair, Reiko Horikawa, Agnès Linglart, Kevin C J Yuen

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Drug design, development and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Current understanding and perspectives on growth and long-acting GH therapy in Japan.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Bradley S MillerDivision of Pediatric Endocrinology, University of Minnesota Medical School, MHealth Fairview Masonic Children's Hospital, Minneapolis, MN, USA.ORCID 0000-0003-3663-5473
Jo BlairDepartment of Paediatric Endocrinology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.ORCID 0000-0003-3128-5574
Reiko HorikawaDivision of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo, Japan.ORCID 0000-0003-3429-3246
Agnès LinglartDepartment of Endocrinology and Diabetes for Children, Hospital Bicêtr Paris Saclay, AP-HP, Le Kremlin-Bicêtre, France.ORCID 0000-0003-3455-002X
Kevin C J YuenDepartments of Neuroendocrinology and Neurosurgery, Barrow Neurological Institute, University of Arizona College of Medicine and Creighton School of Medicine, Phoenix, AZ, USA.ORCID 0000-0002-8169-2728
Alder Hey Children's NHS Foundation Trust · GBBarrow Neurological Institute · USInserm · FRNational Center For Child Health and Development · JPUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth hormone (GH) replacement therapy for growth hormone deficiency (GHD) in children and adults has for over 25 years, until recently, been administered as daily injections. This daily treatment regimen often incurs a burden to patients and caregivers, leading to high rates of non-adherence and, consequently, decreased treatment efficacy outcomes. To address this shortcoming, long-acting growth hormones (LAGHs) have been developed with the aim of reducing the burden of daily injections, thereby potentially improving treatment adherence and outcomes. Somapacitan (Sogroya

Indexed as

Dwarfism, PituitaryHistidineHuman Growth HormoneMannitolPhenolAdultChildGrowth HormoneHumansInsulin-Like Growth Factor ITreatment OutcomeUnited StatesGrowth HormoneHistidineHuman Growth HormoneInsulin-Like Growth Factor IMannitolPhenolsomapacitan(3–6): growth hormoneadherenceadult growth hormone deficiencylong-acting growth hormonepediatric growth hormone deficiency

Identifiers

PMID38333899
PMCPMC10849900
OpenAlexW4391514163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.