ArticleFrontiers in bioengineering and biotechnology2024
Performance of 3D printed porous polyetheretherketone composite scaffolds combined with nano-hydroxyapatite/carbon fiber in bone tissue engineering: a biological evaluation.
Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Nanohydroxyapatite and its composite scaffold for bone tissue engineering application: a systematic review.Journal of materials science. Materials in medicine · 2025Pooled it
- PEEK in modern maxillofacial surgery: clinical applications, limitations and future opportunities.British dental journal · 2026Review
- Graphene oxide-modified PEEK composites: Properties and applications in orthopaedic repair - A review.Journal of orthopaedic translation · 2026Review
- Process-Driven Optimization of FDM Porous PEEK Scaffolds for Alloplastic Bone Grafts.ACS omega · 2025Article
- Preclinical evaluation of lateral interbody fusions using 3D printed PEEK or 3D printed titanium cages.North American Spine Society journal · 2025Article
- 3D printed Gel/PTH@PAHA scaffolds with both enhanced osteogenesis and mechanical properties for repair of large bone defects.Regenerative biomaterials · 2025Article
- Biphasic Calcium Phosphate and Activated Carbon Microparticles in a Plasma Clot for Bone Reconstruction and In Situ Drug Delivery: A Feasibility Study.Materials (Basel, Switzerland) · 2024Article
- Machine Learning and Mendelian Randomization Reveal Molecular Mechanisms and Causal Relationships of Immune-Related Biomarkers in Periodontitis.Mediators of inflammation · 2024Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyetheretherketone (PEEK) has been one of the most promising materials in bone tissue engineering in recent years, with characteristics such as biosafety, corrosion resistance, and wear resistance. However, the weak bioactivity of PEEK leads to its poor integration with bone tissues, restricting its application in biomedical fields. This research effectively fabricated composite porous scaffolds using a combination of PEEK, nano-hydroxyapatite (nHA), and carbon fiber (CF) by the process of fused deposition molding (FDM). The experimental study aimed to assess the impact of varying concentrations of nHA and CF on the biological performance of scaffolds. The incorporation of 10% CF has been shown to enhance the overall mechanical characteristics of composite PEEK scaffolds, including increased tensile strength and improved mechanical strength. Additionally, the addition of 20% nHA resulted in a significant increase in the surface roughness of the scaffolds. The high hydrophilicity of the PEEK composite scaffolds facilitated the
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