Evidence map›Paper›PMID 38333077›Full record

ArticleCritical care explorations2024

Association of Sepsis With Neurologic Outcomes of Adult Patients Treated With Venoarterial Extracorporeal Membrane Oxygnenation.

Chloé Tridon, Delphine Bachelet, Majda El Baied, Philippine Eloy, Sofia Ortuno, Marylou Para, Paul-Henri Wicky, Geoffroy Vellieux, Etienne de Montmollin, Lila Bouadma and 4 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care explorations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Chloé TridonMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Delphine BacheletPhysiologie-Explorations Fonctionnelles, FHU APOLLO, DMU DREAM, Assistance Publique Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Paris, France.
Majda El BaiedPhysiologie-Explorations Fonctionnelles, FHU APOLLO, DMU DREAM, Assistance Publique Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Paris, France.
Philippine EloyPhysiologie-Explorations Fonctionnelles, FHU APOLLO, DMU DREAM, Assistance Publique Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Paris, France.
Sofia OrtunoMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Marylou ParaService de Chirurgie Cardiaque, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France. Université de Paris Cité, INSERM U1148, Paris, France.
Paul-Henri WickyMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Geoffroy VellieuxNeurophysiologie clinique, service de Physiologie-Explorations Fonctionnelles, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Etienne de MontmollinMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Lila BouadmaMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Hana ManceauUniversité de Paris, IAME, INSERM, UMR1137, Paris, France.
Jean-François TimsitMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Katell Peoc'hUniversité de Paris, IAME, INSERM, UMR1137, Paris, France.
Romain SonnevilleMédecine intensive-réanimation, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France.
Université Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNeurologic outcomes of patients under venoarterial extracorporeal membrane oxygenation (VA-ECMO) may be worsened by secondary insults of systemic origin. We aimed to assess whether sepsis, commonly observed during ECMO support, is associated with brain injury and outcomes.

designSingle-center cohort study of the "exposed-non-exposed" type on consecutive adult patients treated by VA-ECMO.

settingMedical ICU of a university hospital, France, 2013-2020. PATIENTS: Patients with sepsis at the time of VA-ECMO cannulation ("sepsis" group) were compared with patients without sepsis ("no sepsis" group). The primary outcome measure was poor functional outcome at 90 days, defined by a score greater than or equal to 4 on the modified Rankin scale (mRS), indicating severe disability or death.

interventionsNone. MEASUREMENTS AND MAIN

resultsA total of 196 patients were included ("sepsis,"

conclusionWe observed a detrimental role of sepsis on neurologic outcomes in the subgroup of patients who had experienced pre-ECMO cardiac arrest, but not in other patients.

Indexed as

brain injuryextracorporeal membrane oxygenationneuron-specific enolaseS100 calcium-binding protein betasepsis

Identifiers

PMID38333077
PMCPMC10852385
OpenAlexW4391654096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.