Evidence map›Paper›PMID 38333018›Full record

ArticleInternational journal of general medicine2024

Efficacy of Fire-Needle Therapy in Improving Neurological Function Following Cerebral Infarction and Its Effect on Intestinal Flora Metabolites.

Yi-Jun Feng, Bing-Quan Wang, Lu-Lu Cao, Li-Ying Dong, Chu-Yi Zhang, Dong-Jian Hu, Zhen Zhou, Jin-Xiu Cao

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yi-Jun Feng *Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People's Republic of China.
Bing-Quan Wang *Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People's Republic of China.
Lu-Lu CaoShanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Li-Ying DongDepartment of Encephalopathy and Acupuncture, Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300250, People's Republic of China.
Chu-Yi ZhangTianjin University of Traditional Chinese Medicine, Tianjin, 301617, People's Republic of China.
Dong-Jian HuTianjin University of Traditional Chinese Medicine, Tianjin, 301617, People's Republic of China.
Zhen ZhouDepartment of Encephalopathy and Acupuncture, Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300250, People's Republic of China.
Jin-Xiu CaoDepartment of Geriatrics, Shanghai Eighth People's Hospital, Shanghai, 200235, People's Republic of China.
Tianjin University of Traditional Chinese Medicine · CNFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine · CNShanghai Eighth People Hospital · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study was to investigate the mechanism of action and clinical efficacy of fire-needle therapy in improving neurological function in patients with acute cerebral infarction (identified as a wind-phlegm-blood stasis syndrome in traditional Chinese medicine). Methods: We included patients diagnosed with acute cerebral infarction (wind-phlegm-blood stasis syndrome) admitted to the Encephalopathy and Acupuncture Center of the Second Affiliated Hospital of Tianjin University of Chinese Medicine. We randomly allocated them into the treatment and control groups, with 45 cases in each group. Acupuncture treatments that focused on regulating the mind and dredging the collaterals were used in the control group, while the treatment group additionally received fire-needle therapy. Our indicators included the National Institutes of Health Stroke Scale (NIHSS) scores, the Fugl-Meyer Assessment (FMA) scale, peripheral blood tumor necrosis factor-α (TNF-α), interleukin-17 (IL-17), hypersensitivity C-reactive protein (hs-CRP), and intestinal metabolites short-chain fatty acids (SCFAs). We measured these indicators before treatment and 14 days after treatment. Results: The post-treatment NIHSS scores of the two groups were significantly reduced ( Conclusion: Fire-needle therapy was effective in upregulating the SCFA content in patients with acute cerebral infarction (wind-phlegm-blood stasis syndrome), inhibiting the level of the inflammatory response, and improving the recovery of neurological functions. Clinical registration number: Registration website link: https://www.chictr.org.cn. Registration date: 2022/9/27. Registration number: ChiCTR2200064122.

Indexed as

acute cerebral infarctionfire-needle therapyshort-chain fatty acidswind-phlegm-blood stasis syndrome

Identifiers

PMID38333018
PMCPMC10850761
OpenAlexW4391482688

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.