ArticleChemical science2024
Single-molecule electrochemical imaging resolves the midpoint potentials of individual fluorophores on nanoporous antimony-doped tin oxide.
Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Single Fluorogens and Orientation-Localization Microscopy for Quantifying Chemical and Biomolecular Dynamics at the Nanoscale.Accounts of chemical research · 2026Article
- The Fantastic Single-Molecule Techniques.Chemical & biomedical imaging · 2026Review
- Recent Developments in Single-Entity Electrochemistry.Analytical chemistry · 2024Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
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Abstract
We report reversible switching of oxazine, cyanine, and rhodamine dyes by a nanoporous antimony-doped tin oxide electrode that enables single-molecule (SM) imaging of electrochemical activity. Since the emissive state of each fluorophore is modulated by electrochemical potential, the number of emitting single molecules follows a sigmoid function during a potential scan, and we thus optically determine the formal redox potential of each dye. We find that the presence of redox mediators (phenazine methosulfate and riboflavin) functions as an electrochemical switch on each dye's emissive state and observe significantly altered electrochemical potential and kinetics. We are therefore able to measure optically how redox mediators and the solid-state electrode modulate the redox state of fluorescent molecules, which follows an electrocatalytic (EC') mechanism, with SM sensitivity over a 900 μm
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Registered trials
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