Evidence map›Paper›PMID 38332440›Full record

Trial reportJournal of general internal medicine2024

Bundling Colorectal Cancer Screening Outreach with Screening for Social Risk in Federally Qualified Health Centers: A Stepped-Wedge Implementation-Effectiveness Study.

Gina R Kruse, Sanja Percac-Lima, Marjanna Barber-Dubois, Madeline E Davies, Daniel A Gundersen, Oanh Ho, Lynette Mascioli, Mehezbin Munshi, Sarah Perry, Deepinder Singh and 3 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Journal of general internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04585919 (Paired Promotion of Colorectal Cancer and Social Determinants of Health Screening), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04585919 nacompletednot on this map

Paired Promotion of Colorectal Cancer and Social Determinants of Health Screening

TypeinterventionalSponsorHarvard School of Public Health (HSPH)Ran2020 to 2022Enrolled26ConditionsColorectal Cancer, Social Determinants of HealthArmsPaired Screening Intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Effectiveness ofCancers · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Gina R KruseDivision of General Internal Medicine, University of Colorado School of Medicine, Aurora, CO, USA. gina.kruse@cuanschutz.edu.ORCID 0000-0002-6681-220X
Sanja Percac-LimaDivision of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.
Marjanna Barber-DuboisManet Community Health Center, Quincy, MA, USA.
Madeline E DaviesKraft Center for Community Health, Massachusetts General Hospital, Boston, MA, USA.
Daniel A GundersenSurvey and Qualitative Methods Core, Dana Farber Cancer Institute, Boston, MA, USA.
Oanh HoHarbor Health Services, Inc., Mattapan, MA, USA.
Lynette MascioliMassachusetts League of Community Health Centers, Boston, MA, USA.
Mehezbin MunshiMassachusetts League of Community Health Centers, Boston, MA, USA.
Sarah PerryHarbor Health Services, Inc., Mattapan, MA, USA.
Deepinder SinghLarner College of Medicine, University of Vermont, Burlington, VT, USA.
Annette ThomasBrockton Neighborhood Health Center, Brockton, MA, USA.
Karen M EmmonsDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Jennifer S HaasDivision of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.
Harvard University · USCommunity Health Center · USMassachusetts General Hospital · USSignature Healthcare Brockton Hospital · USUniversity of Colorado Denver · USUniversity of Vermont · US

Funding

The Implementation Science Center for Cancer Control Equity - Research ProgramP50CA244433 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI EMMONS, KAREN M., TAVERAS BENAVIDEZ, ELSIE MIREYA · 2019 to 2023
$12.5M
American Cancer Society CRP-22-080-01-CTPSNCI NIH HHS P50 CA244433
6 · The paper itself

Abstract

backgroundBundling is combining individual interventions to meet quality metrics. Bundling offers of cancer screening with screening for social determinants of health (SDOH) may enable health centers to assist patients with social risks and yield efficiencies.

objectiveTo measure effects of bundling fecal immunochemical testing (FIT) and SDOH screening in federally qualified health centers (FQHCs).

designClustered stepped-wedge trial.

participantsFour Massachusetts FQHCs randomized to implement bundled FIT-SDOH over 8-week "steps."

interventionOutreach to 50-75-year-olds overdue for CRC screening to offer FIT with SDOH screening. The implementation strategy used facilitation and training for data monitoring and reporting. MAIN MEASURES: Implementation process descriptions, data from facilitation meetings, and CRC and SDOH screening rates. Rates were compared between implementation and control FQHCs in each "step" by fitting generalized linear mixed-effects models with random intercepts for FQHCs, patients, and "step" by FQHC. KEY

resultsFQHCs tailored implementation processes to their infrastructure, workflows, and staffing and prioritized different groups for outreach. Two FQHCs used population health outreach, and two integrated FIT-SDOH within established programs, such as pre-visit planning. Of 34,588 patients overdue for CRC screening, 54% were female; 20% Black, 11% Latino, 10% Asian, and 47% white; 32% had Medicaid, 16% Medicare, 32% private insurance, and 11% uninsured. Odds of CRC screening completion in implementation "steps" compared to controls were higher overall and among groups prioritized for outreach (overall: adjusted odds ratio (aOR) 2.41, p = 0.005; prioritized: aOR 2.88, p = 0.002). Odds of SDOH screening did not differ across "steps."

conclusionsAs healthcare systems are required to conduct more screenings, it is notable that outreach for a long-standing cancer screening requirement increased screening, even when bundled with a newer screening requirement. This outreach was feasible in a real-world safety-net clinical population and may conserve resources, especially compared to more complex or intensive outreach strategies. CLINICAL TRIALS REGISTRATION: NCT04585919.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerAgedFemaleHumansMaleMassachusettsMass ScreeningMiddle AgedOccult BloodSafety-net ProvidersSocial Determinants of HealthUnited Statescolorectal cancercommunity health centersimplementation science.screeningsocial determinants of health

Identifiers

PMID38332440
PMCPMC11116362
OpenAlexW4391658580

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.