Evidence map›Paper›PMID 38332424›Full record

ArticleInternational urology and nephrology2024

Incidence of postoperative cytomegalovirus and BK-polyoma virus infections and graft loss in ABO-incompatible renal transplant recipients: a multicenter retrospective study.

Hirotake Kodama, Shingo Hatakeyama, Tomohiko Matsuura, Mitsuru Saito, Hayato Nishida, Tomoko Hamaya, Shinya Maita, Reiichi Murakami, Hirofumi Tomita, Hisao Saitoh and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Hirotake KodamaDepartment of Urology, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki, Aomori, 036-8562, Japan.
Shingo HatakeyamaDepartment of Advanced Blood Purification Therapy, Hirosaki University Graduate School of Medicine, 5 Zaifu-Cho, Hirosaki, Aomori, 036-8562, Japan. shingoh@hirosaki-u.ac.jp.ORCID http://orcid.org/0000-0002-0026-4079
Tomohiko MatsuuraDepartment of Urology, Iwate Medical University, 1-1-1 Idaidori, Yahaba-Cho, Shiwa-Gun, Morioka, Iwate, 028-3694, Japan.
Mitsuru SaitoDepartment of Urology, Akita University School of Medicine, 1-1-1, Hondo, Akita, 010-8543, Japan.
Hayato NishidaDepartment of Urology, Faculty of Medicine, Yamagata University, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.
Tomoko HamayaDepartment of Urology, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki, Aomori, 036-8562, Japan.
Shinya MaitaDepartment of Urology, Iwate Prefectural Isawa Hospital, 61 Mizusawaryuugababa, Oshu, Iwate, 023-0864, Japan.
Reiichi MurakamiDepartment of Cardiology and Nephrology, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki, Aomori, 036-8562, Japan.
Hirofumi TomitaDepartment of Cardiology and Nephrology, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki, Aomori, 036-8562, Japan.
Hisao SaitohDepartment of Urology, Oyokyo Kidney Research Institute, 90 Kozawayamazaki, Hirosaki, Aomori, 036-8243, Japan.
Norihiko TsuchiyaDepartment of Urology, Faculty of Medicine, Yamagata University, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan.
Tomonori HabuchiDepartment of Urology, Akita University School of Medicine, 1-1-1, Hondo, Akita, 010-8543, Japan.
Wataru ObaraDepartment of Urology, Iwate Medical University, 1-1-1 Idaidori, Yahaba-Cho, Shiwa-Gun, Morioka, Iwate, 028-3694, Japan.
Chikara OhyamaDepartment of Urology, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki, Aomori, 036-8562, Japan.
Hirosaki University · JPAkita University · JPIwate Medical University · JPYamagata University · JPIwate Prefectural Central Hospital · JP

Funding

Japan Society for Aeronautical and Space Sciences 20K09517Japan Society for Aeronautical and Space Sciences 20K18083Japan Society for the Promotion of Science 19H05556
6 · The paper itself

Abstract

objectivesThe current study aimed to examine the incidence of perioperative infections and graft viability in ABO-compatible and ABO-incompatible renal transplant recipients.

methodsWe included 643 living donor renal transplant recipients registered in the Michinoku Renal Transplant Network from 1998 to 2021. Patients were divided into the ABO-compatible and ABO-incompatible kidney transplantation groups. We compared the characteristics of the two groups and evaluated the incidence of postoperative viral infections (cytomegalovirus and BK virus), graft loss-free survival, and overall survival between the two groups.

resultsOf 643 patients, 485 (75%) and 158 (25%) were ABO-compatible and ABO-incompatible renal transplant recipients, respectively. Postoperative viral infections, rituximab use, and plasma exchange were significantly more common in ABO-incompatible than in ABO-compatible transplant recipients. However, there were no significant differences in terms of other background characteristics. The ABO-incompatible group was more likely to develop viral infections than the ABO-compatible group. Graft loss-free survival and overall survival did not significantly differ between the two groups. According to the multivariate Cox regression analysis, ABO compatibility was not significantly associated with graft loss-free survival and overall survival.

conclusionAlthough the incidence of postoperative viral infections in ABO-incompatible renal transplant recipients increased, there was no significant difference in terms of rejection events, graft loss-free survival, and overall survival.

Indexed as

ABO Blood-Group SystemBK VirusBlood Group IncompatibilityCytomegalovirus InfectionsKidney TransplantationPolyomavirus InfectionsPostoperative ComplicationsTumor Virus InfectionsAdultFemaleGraft RejectionGraft SurvivalHumansIncidenceMaleMiddle AgedABO Blood-Group SystemABO-incompatibleInfectionMortalityRejection

Identifiers

PMID38332424
OpenAlexW4392731895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.