Evidence map›Paper›PMID 38332042›Full record

ArticleScientific reports2024

Functional connectivity interacts with visual perceptual learning for visual field recovery in chronic stroke.

Eun Namgung, Yong-Hwan Kim, Eun-Jae Lee, Yuka Sasaki, Takeo Watanabe, Dong-Wha Kang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eun NamgungAsan Institute for Life Sciences, Asan Medical Center, Seoul, South Korea.
Yong-Hwan KimNunaps Inc., Seoul, South Korea.
Eun-Jae LeeDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Yuka SasakiDepartment of Cognitive, Linguistic and Psychological Sciences, Brown University, Providence, USA.
Takeo WatanabeDepartment of Cognitive, Linguistic and Psychological Sciences, Brown University, Providence, USA.
Dong-Wha KangDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. dwkang@amc.seoul.kr.
Asan Medical Center · KRBrown University · USUlsan College · KR

Funding

SYSTEMATIC PSYCHOPHYSICAL INVESTIGATION OF VISUAL LEARNINGR01EY019466 · NEI · BROWN UNIVERSITY · PI Takeo Watanabe · 2009 to 2026
$6.6M
Comprehensive frameworks of perceptual learningR01EY027841 · NEI · BROWN UNIVERSITY · PI Takeo Watanabe · 2018 to 2026
$3.2M
Roles of Non-REM and REM sleep in facilitating visual perceptual learningR01EY031705 · NEI · BROWN UNIVERSITY · PI SASAKI, YUKA · 2021 to 2024
$1.6M
NEI NIH HHS R01 EY019466NEI NIH HHS R01 EY027841NEI NIH HHS R01 EY031705NIH HHS EY031705NIH HHS R01 EY027841
6 · The paper itself

Abstract

A reciprocal relationship between perceptual learning and functional brain changes towards perceptual learning effectiveness has been demonstrated previously; however, the underlying neural correlates remain unclear. Further, visual perceptual learning (VPL) is implicated in visual field defect (VFD) recovery following chronic stroke. We investigated resting-state functional connectivity (RSFC) in the visual cortices associated with mean total deviation (MTD) scores for VPL-induced VFD recovery in chronic stroke. Patients with VFD due to chronic ischemic stroke in the visual cortex received 24 VPL training sessions over 2 months, which is a dual discrimination task of orientation and letters. At baseline and two months later, the RSFC in the ipsilesional, interhemispheric, and contralesional visual cortices and MTD scores in the affected hemi-field were assessed. Interhemispheric visual RSFC at baseline showed the strongest correlation with MTD scores post-2-month VPL training. Notably, only the subgroup with high baseline interhemispheric visual RSFC showed significant VFD improvement following the VPL training. The interactions between the interhemispheric visual RSFC at baseline and VPL led to improvement in MTD scores and largely influenced the degree of VFD recovery. The interhemispheric visual RSFC at baseline could be a promising brain biomarker for the effectiveness of VPL-induced VFD recovery.

Indexed as

StrokeVisual CortexBrainBrain Damage, ChronicHumansMagnetic Resonance ImagingSpatial LearningVisual Fields

Identifiers

PMID38332042
PMCPMC10853510
OpenAlexW4391653909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.