Evidence map›Paper›PMID 38331988›Full record

ArticleScientific reports2024

Collagenase-based wound debridement agent induces extracellular matrix supporting phenotype in macrophages.

Pradipta Banerjee, Amitava Das, Kanhaiya Singh, Savita Khanna, Chandan K Sen, Sashwati Roy

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Pradipta BanerjeeDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 450 Technology Drive, Room#421, Pittsburgh, PA, 15219, USA.
Amitava DasIndiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.
Kanhaiya SinghDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 450 Technology Drive, Room#421, Pittsburgh, PA, 15219, USA.
Savita KhannaDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 450 Technology Drive, Room#421, Pittsburgh, PA, 15219, USA.
Chandan K SenDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 450 Technology Drive, Room#421, Pittsburgh, PA, 15219, USA.
Sashwati RoyDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 450 Technology Drive, Room#421, Pittsburgh, PA, 15219, USA. sash.roy@pitt.edu.
University of Pittsburgh · USMcGowan Institute for Regenerative Medicine · USIndiana University School of Medicine

Funding

Diabetic Foot Ulcer Biofilm Infection and RecurrenceR01DK125835 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GURTNER, GEOFFREY C, SEN, CHANDAN K · 2020 to 2024
$3.5M
Cell Specific Gene Editing to Close Diabetic WoundsR01DK135447 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Chandan K Sen · 2023 to 2026
$2.2M
Mechanisms Underlying Impaired Diabetic Wound HealingR01DK114718 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ROY, SASHWATI · 2018 to 2021
$1.6M
Tissue reprogramming in diabetic wound healingR01DK128845 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROY, SASHWATI, SEN, CHANDAN K · 2021 to 2023
$1.5M
NIDDK NIH HHS R01 DK114718NIDDK NIH HHS R01 DK125835NIDDK NIH HHS R01 DK128845NIDDK NIH HHS R01 DK135447
6 · The paper itself

Abstract

Macrophages assume diverse phenotypes and functions in response to cues from the microenvironment. Earlier we reported an anti-inflammatory effect of Collagenase Santyl

Indexed as

CollagenasesMacrophagesDebridementExtracellular MatrixHumansPhenotypeCollagenases

Identifiers

PMID38331988
PMCPMC10853180
OpenAlexW4391654127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.