Evidence map›Paper›PMID 38330922›Full record

ArticleGerontology2024

Associations of Osteoarthritis with Prevalence and Incidence of Cardiovascular Disease over 10 Years in Community-Dwelling Older Adults: The Sydney Memory and Ageing Study.

Mengjie Zeng, Flavia Cicuttini, Yuan Z Lim, Katherine Samaras, Henry Brodaty, Perminder S Sachdev, John D Crawford, Yuanyuan Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gerontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mengjie ZengSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia, Mengjie.Zeng@monash.edu.
Flavia CicuttiniSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Yuan Z LimSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Katherine SamarasDiabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
Henry BrodatyCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, University of New South Wales Sydney, Kensington, New South Wales, Australia.
Perminder S SachdevCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, University of New South Wales Sydney, Kensington, New South Wales, Australia.
John D CrawfordCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, University of New South Wales Sydney, Kensington, New South Wales, Australia.
Yuanyuan WangSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Monash University · AUGarvan Institute of Medical Research · AUPrince of Wales Hospital · AU

Funding

Medical Research Council 350833
6 · The paper itself

Abstract

introductionThe data are limited for the association between osteoarthritis (OA) and cardiovascular disease (CVD) in community-based older populations and whether there is sex difference. This study aimed to examine the relationship between OA and prevalence and incidence of CVD over 10 years in community-dwelling older adults.

methodsData on self-reported OA, high cholesterol, hypertension, and type 2 diabetes were collected from 1,025 community-dwelling participants aged 70-90 years in the Sydney Memory and Ageing Study. The presence of CVD at baseline was defined as self-reported presence of stroke, heart attack, transient ischaemic attack, angina, aortic aneurysm, or claudication. The incidence of CVD was defined by a combination of incident self-reported CVD or CVD mortality at different follow-up timepoints over 10 years.

resultsAt baseline, 395 (38.5%) participants self-reported OA (252 [44.6%] women, 143 [31.1%] men). Self-reported OA was associated with increased prevalence of CVD in women (OR 1.67, 95% CI 1.12-2.47) but not men (1.26, 0.80-1.98). In the total population, self-reported OA at baseline was associated with increased incidence of CVD at 4 years (OR 1.77, 95% CI 1.10-2.83), 6 years (1.59, 1.03-2.46), 8 years (1.56, 1.02-2.38), and 10 years (1.66, 1.10-2.50), but not at 2 years (1.43, 0.79-2.57). Significant associations were observed in female participants at 4, 8, and 10 years, with no significant associations seen in male participants.

conclusionOA was associated with increased prevalence at baseline and incidence of CVD over 10 years in community-based older adults, especially women. Identifying those with OA to target their cardiovascular risk factors while managing their OA has the potential to reduce the burden of CVD in older people, particularly women.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2OsteoarthritisAgedAgingCohort StudiesFemaleHumansIncidenceIndependent LivingMalePrevalenceRisk FactorsCardiovascular diseaseCardiovascular risk factorsOlder adultsOsteoarthritisWomen

Identifiers

PMID38330922
PMCPMC11006274
OpenAlexW4392664447

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.