Evidence map›Paper›PMID 38330912›Full record

ArticleJournal of the American Chemical Society2024

Targeted Cyclo[8]pyrrole-Based NIR-II Photoacoustic Tomography Probe for Suppression of Orthotopic Pancreatic Tumor Growth and Intra-abdominal Metastases.

Jingqin Chen, Rui Chen, Calvin V Chau, Adam C Sedgwick, Qiang Xue, Tao Chen, Silue Zeng, Ningbo Chen, Kenneth K Y Wong, Liang Song and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Jingqin ChenResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Rui ChenResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Calvin V ChauDepartment of Chemistry, University of Texas at Austin, 105 East 24th Street A5300, Austin, Texas 78712-1224, United States.
Adam C SedgwickDepartment of Chemistry, Kings College London, 7 Trinity Street, London SE1 1DB, U.K.ORCID 0000-0002-3132-2913
Qiang XueResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Tao ChenResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Silue ZengResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Ningbo ChenResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Kenneth K Y WongDepartment of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-3668-3539
Liang SongResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Yaguang RenResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Jian YangDepartment of Hepatobiliary Surgery I, General Surgery Center, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.
Jonathan L SesslerDepartment of Chemistry, University of Texas at Austin, 105 East 24th Street A5300, Austin, Texas 78712-1224, United States.ORCID 0000-0002-9576-1325
Chengbo LiuResearch Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Chinese Academy of Sciences · CNThe University of Texas at Austin · USKing's College - North Carolina · USUniversity of Hong Kong · HKZhujiang Hospital · CN

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
NCI NIH HHS R01 CA068682
6 · The paper itself

Abstract

Pancreatic cancer is highly lethal. New diagnostic and treatment modalities are desperately needed. We report here that an expanded porphyrin, cyclo[8]pyrrole (CP), with a high extinction coefficient (89.16 L/g·cm) within the second near-infrared window (NIR-II), may be formulated with an α

Indexed as

NanoparticlesPancreatic NeoplasmsPhotoacoustic TechniquesAnimalsCell Line, TumorMicePeptides, CyclicPhototherapyPyrrolesTomography, X-Ray Computedcyclic arginine-glycine-aspartic acid peptidePeptides, CyclicPyrroles

Identifiers

PMID38330912
PMCPMC12055259
OpenAlexW4391636384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.