ArticlePublic health2024
Long-term cancer and overall mortality associated with drinking water nitrate in the United States.
Article in Public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Drinking water source and the gut microbiome of 5-year-old children: findings from Gen3G birth cohort.American journal of epidemiology · 2026Article
- Exploring the link between nitrate exposure and thyroid cancer: A nationwide state-level analysis.Journal of the Endocrine Society · 2026Article
- Environmental and societal costs of maize production decrease by addressing the uncertainty in nitrogen rate recommendations.Nature communications · 2026Article
- Epigenetic age acceleration and mortality risk prediction in US adults.GeroScience · 2025Article
- Disinfection byproducts in US drinking water and cancer mortality.International journal of environmental health research · 2025Article
- Association between perchlorate, nitrate, and thiocyanate exposure and kidney stones prevalence in US adults: an analysis based on the national health and nutrition examination survey 2007-2018.BMC public health · 2025Article
- Epigenetic age acceleration and mortality risk prediction in U.S. adults.medRxiv : the preprint server for health sciences · 2024Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesNitrate is a probable carcinogen regulated in drinking water by the US Environmental Protection Agency (EPA) to a maximum contaminant level (MCL) of 10 mg/L nitrate-nitrogen (NO STUDY
designThis study used a population-based retrospective cohort design.
methodsWe analyzed data from 2029 participants of the 2005-2006 National Health and Nutrition Examination Survey followed for mortality until 2019 for a median of 13.9 years. We used Cox proportional hazards regression to estimate the hazard ratio (HR) and 95% confidence interval (CI) for mortality associated with drinking water nitrate, adjusting for covariates that included socio-economic factors and pack-years of cigarette smoking.
resultsDrinking water nitrate was detected in 50.8 % of the samples, had a median concentration of 0.77 mg/L NO
conclusionsLevels of drinking water nitrate may be an overlooked contributor to cancer mortality in the United States.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.