Evidence map›Paper›PMID 38330263›Full record

ArticleJCO precision oncology2024

Safety and Intracranial Activity of Adagrasib in Patients With

Ezra Bernstein, Jia Luo, Kaiwen Wang, Marcelo V Negrao, Pasi A Jänne, Joshua K Sabari

Open access · hybridAbstract read
In one paragraph

Article in JCO precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. KRASFrontiers in oncology · 2026
    Pooled it
  2. Review
  3. Precision Targeting ofInternational journal of molecular sciences · 2026
    Review
  4. Development andTheranostics · 2026
    Article
  5. Adagrasib in the treatment of colorectal cancer.Future oncology (London, England) · 2025
    Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ezra BernsteinLangone Department of Internal Medicine, New York University, New York, NY.ORCID 0000-0003-1911-1969
Jia LuoLowe Center for Thoracic Oncology, Dana-Faber Cancer Institute, Boston, MA.ORCID 0000-0003-3606-827X
Kaiwen WangDivision of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0003-2881-8181
Marcelo V NegraoDepartment of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0001-8938-6699
Pasi A JänneLowe Center for Thoracic Oncology, Dana-Faber Cancer Institute, Boston, MA.ORCID 0000-0002-7821-4928
Joshua K SabariPerlmutter Cancer Center, New York University Langone Health, New York, NY.ORCID 0000-0002-1556-1543
Dana-Farber Cancer Institute · USThe University of Texas MD Anderson Cancer Center · USNew York University · USNYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPiperazinesPyrimidinesAcetonitrilesHumansProto-Oncogene Proteins p21(ras)AcetonitrilesadagrasibKRAS protein, humanPiperazinesProto-Oncogene Proteins p21(ras)Pyrimidines

Identifiers

PMID38330263
PMCPMC10860949
OpenAlexW4391637688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.