Evidence map›Paper›PMID 38330222›Full record

ArticleACS applied materials & interfaces2024

In Vitro and In Vivo Assessment of the Infection Resistance and Biocompatibility of Small-Molecule-Modified Polyurethane Biomaterials.

Li-Chong Xu, Jennifer L Booth, Matthew Lanza, Tugba Ozdemir, Amelia Huffer, Chen Chen, Asma Khursheed, Dongxiao Sun, Harry R Allcock, Christopher A Siedlecki

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Li-Chong XuORCID 0000-0001-6503-0655
Jennifer L Booth
Matthew Lanza
Tugba OzdemirDepartment of Nanoscience and Biomedical Engineering, South Dakota School of Mines and Technology, Rapid City, South Dakota 57701, United States.
Amelia HufferDepartment of Nanoscience and Biomedical Engineering, South Dakota School of Mines and Technology, Rapid City, South Dakota 57701, United States.
Chen ChenDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Asma Khursheed
Dongxiao Sun
Harry R AllcockDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-8822-3457
Christopher A SiedleckiORCID 0000-0003-2163-4099
Pennsylvania State University · USSouth Dakota School of Mines and Technology · US

Funding

Combinatorial Approaches to Improved Blood-contacting Polymer BiomaterialsR01HL153231 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SIEDLECKI, CHRISTOPHER A · 2020 to 2023
$2.6M
NHLBI NIH HHS R01 HL153231
6 · The paper itself

Abstract

Bacterial intracellular nucleotide second messenger signaling is involved in biofilm formation and regulates biofilm development. Interference with the bacterial nucleotide second messenger signaling provides a novel approach to control biofilm formation and limit microbial infection in medical devices. In this study, we tethered small-molecule derivatives of 4-arylazo-3,5-diamino-1

Indexed as

Bacterial InfectionsBiocompatible MaterialsAnimalsBacteriaBacterial AdhesionBiofilmsNucleotidesPolymersPolyurethanesRatsRats, WistarBiocompatible MaterialsNucleotidesPolymersPolyurethanesbiocompatibilityc-di-AMPinfection resistancenucleotidesmall molecule

Identifiers

PMID38330222
PMCPMC12718445
OpenAlexW4391637327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.