Evidence map›Paper›PMID 38330071›Full record

ArticlePloS one2024

Training for endovascular therapy of acute arterial disease and procedure-related complication: An extracorporeally-perfused human cadaver model study.

Viktor Hartung, Anne Marie Augustin, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Florian Kleefeldt, Süleyman Ergün, Dominik Peter, Sven Lichthardt, Thorsten Alexander Bley and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Viktor HartungDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.ORCID 0000-0002-6273-9172
Anne Marie AugustinDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.
Jan-Peter GrunzDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.ORCID 0000-0002-4524-1620
Henner HuflageDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.ORCID 0000-0002-2784-3257
Jan-Lucca HennesDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.
Florian KleefeldtInstitute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.ORCID 0009-0007-7751-0403
Süleyman ErgünInstitute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.
Dominik PeterDepartment of General, Visceral, Transplant, Vascular, and Pediatric Surgery, University Hospital of Würzburg, Würzburg, Germany.
Sven LichthardtDepartment of General, Visceral, Transplant, Vascular, and Pediatric Surgery, University Hospital of Würzburg, Würzburg, Germany.
Thorsten Alexander BleyDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.
Philipp GruschwitzDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.ORCID 0000-0002-2565-8111
Universitätsklinikum Würzburg · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the usability of a recently developed extracorporeally-perfused cadaver model for training the angiographic management of acute arterial diseases and periprocedural complications that may occur during endovascular therapy of the lower extremity arterial runoff. MATERIALS AND

methodsContinuous extracorporeal perfusion was established in three fresh-frozen body donors via inguinal and infragenicular access. Using digital subtraction angiography for guidance, both arterial embolization (e.g., embolization using coils, vascular plugs, particles, and liquid embolic agents) and endovascular recanalization procedures (e.g., manual aspiration or balloon-assisted embolectomy) as well as various embolism protection devices were tested. Furthermore, the management of complications during percutaneous transluminal angioplasty, such as vessel dissection and rupture, were exercised by implantation of endovascular dissection repair system or covered stents. Interventions were performed by two board-certified interventional radiologists and one resident with only limited angiographic experience.

resultsStable extracorporeal perfusion was successfully established on both thighs of all three body donors. Digital subtraction angiography could be performed reliably and resulted in realistic artery depiction. The model allowed for repeatable training of endovascular recanalization and arterial embolization procedures with typical tactile feedback in a controlled environment. Furthermore, the handling of more complex angiographic devices could be exercised. Whereas procedural success was be ascertained for most endovascular interventions, thrombectomies procedures were not feasible in some cases due to the lack of inherent coagulation.

conclusionThe presented perfusion model is suitable for practicing time-critical endovascular interventions in the lower extremity runoff under realistic but controlled conditions.

Indexed as

Endovascular ProceduresVascular DiseasesAngioplastyArteriesCadaverHumansRetrospective StudiesStentsTreatment Outcome

Identifiers

PMID38330071
PMCPMC10852297
OpenAlexW4391641029

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.