SynthesisPloS one2024
A systematic review of oral wound healing indices.
Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of clinical effectiveness between tissue adhesives and sutures for wound closure in periodontal flap surgery: a systematic review and meta-analysis.Frontiers in oral health · 2025Pooled it
- The effect of bioactive membrane in alveolar ridge preservation: A double-blind randomized clinical trial.Journal of periodontology · 2026Trial
- Effect of diode laser biostimulation on implant stability, post-surgical inflammation, and bone healing in immediate implant in the maxillary premolars. A randomized double-blind trial.Clinical oral investigations · 2026Trial
- Effect of platelet-rich fibrin on microperfusion during early socket healing: a randomized controlled clinical trial.Clinical oral investigations · 2025Trial
- Article
- "Beyond the scale: body mass index as a hidden player in post-extraction complications".BMC oral health · 2026Observational
- Soft Tissue Healing After Post-Extractive Alveolar Ridge Reconstruction Using a Magnesium Membrane-Based Regenerative Approach: A Preliminary Study.Journal of functional biomaterials · 2026Article
- Innovations in microsurgery: The role of non-invasive blood perfusion imaging-A review and framework.Clinical advances in periodontics · 2026Review
- Amniotic membrane for oral surgical defect coverage: A clinical study.Bioinformation · 2026Article
- Evaluation of postoperative bleeding and pain following tooth extraction in patients using direct oral anticoagulants: a prospective case-control study with blinded evaluation.BMC oral health · 2025Article
- Elysee Exosome Versus Cellbooster Lift in Oral Wound Healing.Plastic and reconstructive surgery. Global open · 2025Article
- Assessment of the relationship between sense of coherence and surgery-related oral wound healing by using a contemporary scale: a prospective cohort study.BMC oral health · 2025Observational
- Effect of a buried knot in the healing process of dental extraction sites: a prospective study in cats.Journal of feline medicine and surgery · 2025Article
- Bacterial colonization of bone substitute materials used in oral surgery: mechanisms, clinical implications, and preventive strategies-A narrative review.Frontiers in microbiology · 2025Review
- The tooth transformer® revolution: autologous dentin biomaterials and platelet concentrates in oral regeneration. A parallel narrative systematic review.Frontiers in dental medicine · 2025Review
- Effects of Hyaluronic Acid Gel on Initial Wound Healing Following Tooth Extraction and Crown Lengthening Procedures: A Retrospective Analysis.Clinical, cosmetic and investigational dentistry · 2025Article
- Introduction of "MAPS" wound healing index and its correlation with guided bone regeneration outcome.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing monitoring for abnormality identification and intervention is crucial to securing a successful surgical outcome. Indices have been used to summarize the degree of healing. Given the increasing frequency of regenerative procedures which preserve dentition and implant stability, and the higher esthetic demands, an appraisal of the available indices is needed to identify the current knowledge gap. This study aimed to systematically review published oral wound healing indices and scores. MATERIALS AND
methodsA complete literature electronic search in 5 databases was conducted by two reviewers. A combination of keywords related to oral wound healing was used.
resultsA total of 11 articles were included in the evaluation of various procedures (conventional periodontal procedures, guided tissue regeneration, soft tissue reconstruction procedures, and tooth extractions), at different time points (1 day to 12 weeks), with a focus on diverse clinical signs and symptoms. Frequently evaluated parameters included wound dehiscence/epithelialization (91%), tissue color (redness) (73%), suppuration (55%), swelling/edema (55%), and hemostasis (55%). Other less commonly used parameters include esthetics-related and patient-centered outcomes.
conclusionThe available indices evaluate a diverse group of subjective clinical signs and symptoms to estimate the underlying biological healing events and assess the degree of clinical success. The majority of the included indices are not validated. Quantitative and objective subclinical parameters including blood perfusion, biomaterial stability, and completeness of epithelialization, are needed for customized wound healing care and better outcome prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.