Evidence map›Paper›PMID 38329792›Full record

ArticleJMIR formative research2024

A Digitally Enabled Combined Lifestyle Intervention for Weight Loss: Pilot Study in a Dutch General Population Cohort.

Rahul Gannamani, José Castela Forte, Pytrik Folkertsma, Sven Hermans, Sridhar Kumaraswamy, Sipko van Dam, Niels Chavannes, Hendrikus van Os, Hanno Pijl, Bruce H R Wolffenbuttel

Open access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. [Application of Digital Nutrition Technologies in Adult Weight Management].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rahul Gannamani *Ancora Health BV, Groningen, Netherlands.ORCID https://orcid.org/0000-0003-4576-2271
José Castela Forte *Ancora Health BV, Groningen, Netherlands.ORCID https://orcid.org/0000-0001-9273-0702
Pytrik FolkertsmaAncora Health BV, Groningen, Netherlands.ORCID https://orcid.org/0000-0003-1823-8706
Sven HermansAncora Health BV, Groningen, Netherlands.ORCID https://orcid.org/0009-0005-4878-4574
Sridhar KumaraswamyAncora Health BV, Groningen, Netherlands.ORCID https://orcid.org/0000-0002-6309-891X
Sipko van DamAncora Health BV, Groningen, Netherlands.ORCID https://orcid.org/0000-0001-9204-0197
Niels ChavannesDepartment of Public Health and Primary Care, Leiden University Medical Centre, Leiden University, Leiden, Netherlands.ORCID https://orcid.org/0000-0002-8607-9199
Hendrikus van OsDepartment of Public Health and Primary Care, Leiden University Medical Centre, Leiden University, Leiden, Netherlands.ORCID https://orcid.org/0000-0002-8911-8608
Hanno PijlDepartment of Endocrinology, Leiden University Medical Center, Leiden University, Leiden, Netherlands.ORCID https://orcid.org/0000-0002-3076-1551
Bruce H R WolffenbuttelDepartment of Endocrinology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.ORCID https://orcid.org/0000-0001-9262-6921
University Medical Center Groningen · NLLeiden University · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOverweight and obesity rates among the general population of the Netherlands keep increasing. Combined lifestyle interventions (CLIs) focused on physical activity, nutrition, sleep, and stress management can be effective in reducing weight and improving health behaviors. Currently available CLIs for weight loss (CLI-WLs) in the Netherlands consist of face-to-face and community-based sessions, which face scalability challenges. A digitally enabled CLI-WL with digital and human components may provide a solution for this challenge; however, the feasibility of such an intervention has not yet been assessed in the Netherlands.

objectiveThe aim of this study was two-fold: (1) to determine how weight and other secondary cardiometabolic outcomes (lipids and blood pressure) change over time in a Dutch population with overweight or obesity and cardiometabolic risk participating in a pilot digitally enabled CLI-WL and (2) to collect feedback from participants to guide the further development of future iterations of the intervention.

methodsParticipants followed a 16-week digitally enabled lifestyle coaching program rooted in the Fogg Behavior Model, focused on nutrition, physical activity, and other health behaviors, from January 2020 to December 2021. Participants could access the digital app to register and track health behaviors, weight, and anthropometrics data at any time. We retrospectively analyzed changes in weight, blood pressure, and lipids for remeasured users. Surveys and semistructured interviews were conducted to assess critical positive and improvement points reported by participants and health care professionals.

resultsOf the 420 participants evaluated at baseline, 53 participated in the pilot. Of these, 37 (70%) were classified as overweight and 16 (30%) had obesity. Mean weight loss of 4.2% occurred at a median of 10 months postintervention. The subpopulation with obesity (n=16) showed a 5.6% weight loss on average. Total cholesterol decreased by 10.2% and low-density lipoprotein cholesterol decreased by 12.9% on average. Systolic and diastolic blood pressure decreased by 3.5% and 7.5%, respectively. Participants identified the possibility of setting clear action plans to work toward and the multiple weekly touch points with coaches as two of the most positive and distinctive components of the digitally enabled intervention. Surveys and interviews demonstrated that the digital implementation of a CLI-WL is feasible and well-received by both participants and health care professionals.

conclusionsAlbeit preliminary, these findings suggest that a behavioral lifestyle program with a digital component can achieve greater weight loss than reported for currently available offline CLI-WLs. Thus, a digitally enabled CLI-WL is feasible and may be a scalable alternative to offline CLI-WL programs. Evidence from future studies in a Dutch population may help elucidate the mechanisms behind the effectiveness of a digitally enabled CLI-WL.

Indexed as

datadigitaldigital healthFogg Behavior Modelinterventionlifestyle interventionobesityoverweightpilotpreventionweightweight loss

Identifiers

PMID38329792
PMCPMC10884913
OpenAlexW4387022972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.