Evidence map›Paper›PMID 38329543›Full record

ArticleBrain structure & function2024

Characterization of Sonic Hedgehog transcripts in the adult mouse brain: co-expression with neuronal and oligodendroglial markers.

Mariagiovanna Russo, Giuliana Pellegrino, Hélène Faure, Linda Tirou, Ariane Sharif, Martial Ruat

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain structure & function, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mariagiovanna RussoCNRS, Paris-Saclay University, UMR-9197, Neuroscience Paris-Saclay Institute, 91400, Saclay, France.
Giuliana PellegrinoCNRS, Paris-Saclay University, UMR-9197, Neuroscience Paris-Saclay Institute, 91400, Saclay, France.
Hélène FaureCNRS, Paris-Saclay University, UMR-9197, Neuroscience Paris-Saclay Institute, 91400, Saclay, France.
Linda TirouCNRS, Paris-Saclay University, UMR-9197, Neuroscience Paris-Saclay Institute, 91400, Saclay, France.
Ariane SharifUniv. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience and Cognition, UMR-S 1172, FHU 1000 Days for Health, Lille, France.
Martial RuatCNRS, Paris-Saclay University, UMR-9197, Neuroscience Paris-Saclay Institute, 91400, Saclay, France. martial.ruat@cnrs.fr.
Centre National de la Recherche Scientifique · FRUniversité Paris-Saclay · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the adult mammalian brain, astrocytes are proposed to be the major Sonic Hedgehog (Shh)-responsive cells. However, the sources of the Shh molecule mediating activation of the pathway are still poorly characterized. The present work investigates the distribution and phenotype of cells expressing Shh mRNA in the adult mouse brain. Using single-molecule fluorescent in situ hybridization (smfISH), we report much broader expression of Shh transcripts in almost all brain regions than originally reported. We identify Shh mRNA in HuC/D

Indexed as

Hedgehog ProteinsNeuronsAnimalsBrainIn Situ Hybridization, FluorescenceMammalsMiceRNA, MessengerHedgehog ProteinsRNA, MessengerMultiple sclerosisNeurodegenerative diseasesPatchedRNAscopeShhSmoothened

Identifiers

PMID38329543
PMCPMC10978748
OpenAlexW4391647891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.