Evidence map›Paper›PMID 38329230›Full record

ArticleChemical communications (Cambridge, England)2024

Oleic acid differentially affects lipid droplet storage of

Hannah B Castillo, Sydney O Shuster, Lydia H Tarekegn, Caitlin M Davis

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Sequential Fractionation ofFoods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hannah B CastilloDepartment of Chemistry, Yale University, New Haven, Connecticut, 06511, USA. c.davis@yale.edu.ORCID http://orcid.org/0009-0008-8516-638X
Sydney O ShusterDepartment of Chemistry, Yale University, New Haven, Connecticut, 06511, USA. c.davis@yale.edu.ORCID http://orcid.org/0000-0003-0996-6779
Lydia H TarekegnDepartment of Chemistry, Yale University, New Haven, Connecticut, 06511, USA. c.davis@yale.edu.
Caitlin M DavisDepartment of Chemistry, Yale University, New Haven, Connecticut, 06511, USA. c.davis@yale.edu.ORCID http://orcid.org/0000-0003-4340-4577
Yale University · US

Funding

PREDOCTORAL PROGRAM IN BIOPHYSICST32GM008283 · NIGMS · YALE UNIVERSITY · PI XIONG, YONG · 1988 to 2022
$10.5M
Predoctoral Program in BiophysicsT32GM149438 · NIGMS · YALE UNIVERSITY · PI Yong Xiong, Elsa Chui Ying Yan · 2023 to 2026
$2.6M
Protein Structural Dynamics in Living CellsR35GM151146 · NIGMS · YALE UNIVERSITY · PI Caitlin Davis · 2023 to 2026
$1.7M
NIGMS NIH HHS R35 GM151146NIGMS NIH HHS T32 GM008283NIGMS NIH HHS T32 GM149438
6 · The paper itself

Abstract

Lipogenesis is a vital but often dysregulated metabolic pathway. Here we use optical photothermal infrared imaging to quantify lipogenesis rates of isotopically labelled oleic acid and glucose concomitantly in live cells. In hepatocytes, but not adipocytes, we find that oleic acid feeding at 60 μM increases the number and size of lipid droplets (LDs) while simultaneously inhibiting storage of

Indexed as

Lipid DropletsOleic AcidAdipocytesHepatocytesLipid MetabolismLipogenesisOleic Acid

Identifiers

PMID38329230
PMCPMC10939124
OpenAlexW4391347979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.