Evidence map›Paper›PMID 38328913›Full record

ArticleCirculation. Cardiovascular quality and outcomes2024

Impact of Residential Social Deprivation on Prediction of Heart Failure in Patients With Type 2 Diabetes: External Validation and Recalibration of the WATCH-DM Score Using Real World Data.

Salil V Deo, Sadeer Al-Kindi, Issam Motairek, David McAllister, Anoop S V Shah, Yakov E Elgudin, Eiran Z Gorodeski, Salim Virani, Mark C Petrie, Sanjay Rajagopalan and 1 more

Abstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Relative Deprivation and Health Among Chinese Adults: The Mediating Role of Subjective Well-Being.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Salil V Deo *Surgical Services, Louis Stokes Cleveland VA Medical Center, Cleveland, OH (S.V.D., Y.E.E.).ORCID 0000-0002-4729-1461
Sadeer Al-Kindi *Division of Cardiovascular Prevention and Wellness, DeBakey Heart and Vascular Center, Houston Methodist, Houston, TX (S.A.-K.).ORCID 0000-0002-1122-7695
Issam MotairekHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH (I.M., E.Z.G., S.R.).ORCID 0000-0003-3294-8659
David McAllisterSchool of Health and Wellbeing (S.V.D., D.M.), University of Glasgow, United Kingdom.ORCID 0000-0003-3550-1764
Anoop S V ShahLondon School of Hygiene and Tropical Medicine, London, United Kingdom (A.S.V.S.).ORCID 0000-0002-2825-3419
Yakov E ElgudinSurgical Services, Louis Stokes Cleveland VA Medical Center, Cleveland, OH (S.V.D., Y.E.E.).ORCID 0000-0002-5249-1820
Eiran Z GorodeskiHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH (I.M., E.Z.G., S.R.).ORCID 0000-0003-3756-8831
Salim ViraniThe Aga Khan University, Karachi, Pakistan (S.V.).ORCID 0000-0001-9541-6954
Mark C PetrieBHF Cardiovascular Research Center, School of Cardiovascular and Metabolic Health (M.C.P., N.S.), University of Glasgow, United Kingdom.ORCID 0000-0002-6333-9496
Sanjay RajagopalanHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH (I.M., E.Z.G., S.R.).ORCID 0000-0001-6669-8163
Naveed SattarBHF Cardiovascular Research Center, School of Cardiovascular and Metabolic Health (M.C.P., N.S.), University of Glasgow, United Kingdom.ORCID 0000-0002-1604-2593

Funding

ACHIEVE P3 - CHDP50MD017351 · NIMHD · WAYNE STATE UNIVERSITY · PI LANFEAR, DAVID E · 2021 to 2025
$21.1M
NIMHD NIH HHS P50 MD017351
6 · The paper itself

Abstract

backgroundPatients with type 2 diabetes are at risk of heart failure hospitalization. As social determinants of health are rarely included in risk models, we validated and recalibrated the WATCH-DM score in a diverse patient-group using their social deprivation index (SDI).

methodsWe identified US Veterans with type 2 diabetes without heart failure that received outpatient care during 2010 at Veterans Affairs medical centers nationwide, linked them to their SDI using residential ZIP codes and grouped them as SDI <20%, 21% to 40%, 41% to 60%, 61% to 80%, and >80% (higher values represent increased deprivation). Accounting for all-cause mortality, we obtained the incidence for heart failure hospitalization at 5 years follow-up; overall and in each SDI group. We evaluated the WATCH-DM score using the C statistic, the Greenwood Nam D'Agostino test χ

resultsIn 1 065 691 studied patients (mean age 67 years, 25% Black and 6% Hispanic patients), the 5-year incidence of heart failure hospitalization was 5.39%. In SDI group 1 (least deprived) and 5 (most deprived), the 5-year heart failure hospitalization was 3.18% and 11%, respectively. The score C statistic was 0.62; WATCH-DM systematically overestimated heart failure risk in SDI groups 1 to 2 (expected/observed ratios, 1.38 and 1.36, respectively) and underestimated the heart failure risk in groups 4 to 5 (expected/observed ratios, 0.95 and 0.80, respectively). Graphical evaluation demonstrated that the recalibration of WATCH-DM using an SDI group-based correction factor improved predictive capabilities as supported by reduction in the χ

conclusionsIncluding social determinants of health to recalibrate the WATCH-DM score improved risk prediction highlighting the importance of including social determinants in future clinical risk prediction models.

Indexed as

Diabetes Mellitus, Type 2Heart FailureAgedHumansPatientsRisk FactorsSocial Deprivationcalibrationcardiovascular diseaseheart failuremyocardial infarctionsocial deprivation

Identifiers

PMID38328913
PMCPMC11093755

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.