ArticleNorthern clinics of Istanbul2023
Ultrasonographic evaluation of muscle thickness in female patients with fibromyalgia and its relationship with clinical parameters.
Article in Northern clinics of Istanbul, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07649824 (Isokinetic Knee Flexor and Extensor Strength, Torque, Ultrasonographic Muscle Thickness, Serum Vitamin D Levels, and Sleep Quality in Female Patients With Fibromyalgia Syndrome), which is not on this map. Cited by 6 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Isokinetic Knee Flexor and Extensor Strength, Torque, Ultrasonographic Muscle Thickness, Serum Vitamin D Levels, and Sleep Quality in Female Patients With Fibromyalgia Syndrome: A Case-Control Study
Who cites it
6 citing papers in PubMed.
- Changes in the mechanical properties and pressure pain thresholds of muscles in patients with fibromyalgia and their relationship with clinical parameters: a case-control study.European journal of applied physiology · 2026Article
- Upper extremity muscle thickness and grip strength following a boccia-based intervention in hemiparetic individuals.BMC sports science, medicine & rehabilitation · 2026Article
- Analysis of muscle architecture variables and their relationship with functional capacity in patients with fibromyalgia: A cross-sectional study.Therapeutic advances in musculoskeletal disease · 2026Article
- Skin layer thickness, muscle elasticity and their effects on pain level in fibromyalgia patients.Clinics (Sao Paulo, Brazil) · 2025Article
- Evaluation of abdominal and lumbar multifidus muscles thickness and relation to endurance, pain, fatigue and functional mobility in patients with Fibromyalgia syndrome: a case-control study.Rheumatology international · 2025Article
- Evaluation of sarcopenia in female patients with fibromyalgia syndrome: an ultrasonographic approach.Frontiers in medicine · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to compare the ultrasonographic thickness of selected major muscles of patients with fibromyalgia syndrome (FMS) and asymptomatic control subjects and to evaluate the relationship between muscle thickness and muscle strength, physical performance, kinesiophobia, and clinical variables.
methodsTwenty-two FMS patients and 18 asymptomatic control cases who applied to the physical medicine and rehabilitation outpatient clinic were included. The thickness of the gastrocnemius medialis/lateralis, trapezius, and upper arm muscle was evaluated with ultrasonography. Muscle strength was evaluated with hand grip strength, muscle performance with chair stand test (CST), walking performance with 10 m walking test, disease severity with Fibromyalgia Impact Questionnaire-Revised, pain severity with VAS, and kinesiophobia with TAMPA kinesiophobia scale.
resultsThe mean thickness values of all the muscles measured were significantly decreased in the FMS group compared with the control (p<0.05). There were positive correlations between gastrocnemius medialis/lateralis and upper arm muscle thickness with hand grip strength (p<0.01, r=0.602, r=0.663, r=0.567, respectively) and positive correlations between gastrocnemius medialis/lateralis muscle thickness with CST (p<0.05, r=0.507, r=0.512, respectively). TAMPA was significantly negatively correlated with gastrocnemius medialis/lateralis and upper arm muscle thickness.
conclusionMuscle thickness, strength, and performance decrease in FMS patients. This reduction in muscle strength, performance, and size is associated with kinesiophobia. Strengthening exercises should be included in the management of FMS patients. However, caution should be exercised when prescribing exercises that require extreme muscle performance, considering that it may cause kinesiophobia.
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