ArticleNorthern clinics of Istanbul2023
The importance of inflammatory biomarkers in ischemic stroke patients with carotid artery stenosis.
Article in Northern clinics of Istanbul, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis.Frontiers in neurology · 2025Pooled it
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3 authors.
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Abstract
objectiveThis study aims to investigate inflammatory markers and their relationship with the degree of stenosis in ischemic stroke patients with carotid artery stenosis.
methodsThis retrospective case-control study was conducted with 70 newly diagnosed ischemic stroke patients and 70 age- and gender-matched healthy controls. Laboratory analyses were carried out including serum hemogram, biochemistry profiles, erythrocyte sedimentation rate, and C-reactive protein (CRP). Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-high-density lipoprotein cholesterol ratio (MHR) values were calculated, and compared between the patients and healthy controls. Patients were divided into two groups according to the degree of arterial carotid stenosis. The degree of carotid stenosis was <50% in Group 1 and it was 50% and above in Group 2.
resultsIn the patient group, neutrophil, monocyte, MPV, CRP, sedimentation, MHR, PLR, and NLR levels were significantly higher than the control group. There was no significant correlation between the level of carotid stenosis and inflammatory biomarkers. There was a significant correlation between the presentation NIHSS value and CRP, PLR, and NLR values.
conclusionInflammatory biomarker values were higher in stroke patients with carotid artery stenosis than in healthy individuals. However, they should neither be used to predict the degree of carotid artery stenosis.
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