Evidence map›Paper›PMID 38328511›Full record

ArticleTherapeutic advances in infectious disease

Re-estimation of the burden of serious fungal diseases in Uganda.

Felix Bongomin, Richard Kwizera, Martha Namusobya, Norman van Rhijn, Irene Andia-Biraro, Bruce J Kirenga, David B Meya, David W Denning

Abstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felix BongominDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.ORCID https://orcid.org/0000-0003-4515-8517
Richard KwizeraInfectious Diseases Institute, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-5270-3539
Martha NamusobyaDepartment of Clinical Epidemiology and Biostatistics, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Norman van RhijnManchester Fungal Infection Group, Division of Evolution, Infection and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Irene Andia-Biraro
Bruce J KirengaDepartment of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
David B MeyaInfectious Diseases Institute, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
David W DenningManchester Fungal Infection Group, CTF Building, The University of Manchester, Grafton Street, Manchester M13 9NT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It is of utmost importance to monitor any change in the epidemiology of fungal diseases that may arise from a change in the number of the at-risk population or the availability of local data. Objective: We sought to update the 2015 publication on the incidence and prevalence of serious fungal diseases in Uganda. Methods: Using the Leading International Fungal Education methodology, we reviewed published data on fungal diseases and drivers of fungal diseases in Uganda. Regional or global data were used where there were no Ugandan data. Results: With a population of ~45 million, we estimate the annual burden of serious fungal diseases at 4,099,357 cases (about 9%). We estimated the burden of candidiasis as follows: recurrent Conclusion: Serious fungal diseases affect nearly 9% of Ugandans every year. Tuberculosis and HIV remain the most important predisposition to acute fungal infection necessitating accelerated preventive, diagnostic, and therapeutic interventions for the management of these diseases.

Indexed as

chronic pulmonary aspergillosiscryptococcal meningitisfungal diseasesUganda

Identifiers

PMID38328511
PMCPMC10848809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.