Evidence map›Paper›PMID 38328253›Full record

ArticlebioRxiv : the preprint server for biology2024

Sex-specific and Developmental Effects of Early Life Adversity on Stress Reactivity are Rescued by Postnatal Knockdown of 5-HT

Rushell Dixon, Lauren Malave, Rory Thompson, Serena Wu, Yifei Li, Noah Sadik, Christoph Anacker

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rushell Dixon
Lauren Malave
Rory Thompson
Serena Wu
Yifei Li
Noah Sadik
Christoph Anacker
Research Foundation For Mental Hygiene · USColumbia University Irving Medical Center · US

Funding

IDENTIFYING CELLULAR AND MOLECULAR SUBSTRATES OF TREATMENT-RESISTANT DEPRESSION.R00MH108719 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ANACKER, CHRISTOPH · 2019 to 2021
$889k
NIMH NIH HHS R00 MH108719
6 · The paper itself

Abstract

Early Life Adversity (ELA) predisposes to stress hypersensitivity in adulthood, but neurobiological mechanisms that protect from the enduring effects of ELA are poorly understood. Serotonin 1A (5HT

Identifiers

PMID38328253
PMCPMC10849559
OpenAlexW4391116028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.