Evidence map›Paper›PMID 38328214›Full record

ArticlebioRxiv : the preprint server for biology2024

Maternal histone methyltransferases antagonistically regulate monoallelic expression in

Bryan Sands, Soo R Yun, Junko Oshima, Alexander R Mendenhall

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Bryan Sands
Soo R Yun
Junko Oshima
Alexander R MendenhallORCID 0000-0002-4716-7671

Funding

University of Washington Nathan Shock Center of Excellence in the Basic Biology of AgingP30AG013280 · NIA · UNIVERSITY OF WASHINGTON · PI Maitreya J Dunham · 1995 to 2026
$27.1M
International Registry of Werner SyndromeR01CA210916 · NCI · UNIVERSITY OF WASHINGTON · PI JUNKO OSHIMA · 2016 to 2026
$3.8M
Understanding the antagonistic role of proteostasis in Alzheimer disease and cancer.R01CA219460 · NCI · UNIVERSITY OF WASHINGTON · PI MENDENHALL, ALEXANDER RICHARD · 2018 to 2022
$2.2M
NCI NIH HHS R01 CA210916NCI NIH HHS R01 CA219460NIA NIH HHS P30 AG013280
6 · The paper itself

Abstract

Undefined epigenetic programs act to probabilistically silence individual autosomal alleles, generating unique individuals, even from genetic clones. This sort of random monoallelic expression can explain variation in traits and diseases that differences in genes and environments cannot. Here, we developed the nematode

Identifiers

PMID38328214
PMCPMC10849558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.