ArticlebioRxiv : the preprint server for biology2024
A CANCER PERSISTENT DNA REPAIR CIRCUIT DRIVEN BY MDM2, MDM4 (MDMX), AND MUTANT P53 FOR RECRUITMENT OF MDC1 AND 53BP1 TO CHROMATIN.
Viola Ellison, Alla Polotskaia, Gu Xiao, Pamella Leybengrub, Weigang Qiu, Rusia Lee, Ronald Hendrickson, Wenwei Hu, Jill Bargonetti
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors at 4 institutions in 1 country.
Viola EllisonHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.ORCID 0000-0002-4275-5570 Alla PolotskaiaHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.
Gu XiaoHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.
Pamella LeybengrubHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.
Weigang QiuHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.ORCID 0000-0003-4585-1872 Rusia LeeHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.ORCID 0000-0002-5376-1888 Ronald HendricksonUniversity of Miami, Miami, FL.
Wenwei HuRutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ.
Jill BargonettiHunter College, The Department of Biological Sciences, Belfer Research Building, New York, NY.ORCID 0000-0003-2692-0991 Hunter College · USThe Graduate Center, CUNY · USRutgers, The State University of New Jersey · USUniversity of Miami · US
Funding
TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221704 · NCI · HUNTER COLLEGE · PI Joel Erblich, Jennifer S Ford · 2018 to 2026
$10.6MGain-of-function mutant p53 and metabolic reprogramming in colorectal cancerR01CA260837 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI FENG, ZHAOHUI, HU, WENWEI · 2021 to 2025
$2.2MThe regulation of mutant p53 protein accumulation in cancer: molecular basis and therapeutic potentialR01CA229257 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI FENG, ZHAOHUI · 2021 to 2025
$2.0MThe role of leukemia inhibitory factor in colorectal cancerR01CA260838 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Wenwei Hu · 2022 to 2026
$1.9MThe Role of the Mutant p53-PARP-MCM Pathway in Triple Negative Breast CancerR01CA239603 · NCI · HUNTER COLLEGE · PI BARGONETTI, JILL E. · 2020 to 2024
$1.8MNCI NIH HHS R01 CA229257NCI NIH HHS R01 CA239603NCI NIH HHS R01 CA260837NCI NIH HHS R01 CA260838NCI NIH HHS U54 CA221704
6 · The paper itselfAbstract
The influence of the metastasis promoting proteins mutant p53 (mtp53) and MDM2 on
Identifiers
PMID38328189
PMCPMC10849484
OpenAlexW4391172819
What OpenQuestion holds
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LicenceCC BY-NC
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