Evidence map›Paper›PMID 38328137›Full record

ArticlebioRxiv : the preprint server for biology2024

Stronger evidence for relaxed selection than adaptive evolution in high-elevation animal mtDNA.

Erik N K Iverson, Abby Criswell, Justin C Havird

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Erik N K IversonDepartment of Integrative Biology, the University of Texas at Austin, Austin, TX, United States.ORCID 0000-0002-3756-9511
Abby CriswellDepartment of Integrative Biology, the University of Texas at Austin, Austin, TX, United States.
Justin C HavirdDepartment of Integrative Biology, the University of Texas at Austin, Austin, TX, United States.
The University of Texas at Austin · US

Funding

Causes and Consequences of Mitochondrial MutationsR35GM142836 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI HAVIRD, JUSTIN C · 2021 to 2025
$2.0M
NIGMS NIH HHS R35 GM142836
6 · The paper itself

Abstract

Mitochondrial (mt) genes are the subject of many adaptive hypotheses due to the key role of mitochondria in energy production and metabolism. One widespread adaptive hypothesis is that selection imposed by life at high elevation leads to the rapid fixation of beneficial alleles in mtDNA, reflected in the increased rates of mtDNA evolution documented in many high-elevation species. However, the assumption that fast mtDNA evolution is caused by positive, rather than relaxed purifying selection has rarely been tested. Here, we calculated the

Identifiers

PMID38328137
PMCPMC10849488
OpenAlexW4391151009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.