Evidence map›Paper›PMID 38328098›Full record

ArticlebioRxiv : the preprint server for biology2024

CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development.

Emily A Bulger, Todd C McDevitt, Benoit G Bruneau

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emily A BulgerGladstone Institutes, San Francisco, CA.ORCID 0000-0003-2967-1994
Todd C McDevittGladstone Institutes, San Francisco, CA.ORCID 0000-0002-8905-4931
Benoit G BruneauGladstone Institutes, San Francisco, CA.ORCID 0000-0002-0804-7597
Gladstone Institutes · US

Funding

PREDOCTORAL TRAINING IN DEVELOPMENTAL BIOLOGYT32HD007470 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Todd Nystul · 1994 to 2026
$7.7M
Early Cardiac ProgenitorsR01HL114948 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI Benoit Gaetan Bruneau · 2013 to 2026
$7.5M
Gene regulatory networks for heart developmentR01HL155906 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN · 2021 to 2024
$2.4M
NHLBI NIH HHS R01 HL114948NHLBI NIH HHS R01 HL155906NICHD NIH HHS T32 HD007470
6 · The paper itself

Abstract

Proper regulation of gene dosage is critical for the development of the early embryo and the extraembryonic tissues that support it. Specifically, loss of

Indexed as

allantoisCDX2extraembryonic mesodermgastrulationgastruloid

Identifiers

PMID38328098
PMCPMC10849648
OpenAlexW4391263465

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.