Evidence map›Paper›PMID 38328075›Full record

ArticlebioRxiv : the preprint server for biology2024

Robin E Kruger, Tristan Frum, A Sophie Brumm, Stephanie L Hickey, Kathy K Niakan, Farina Aziz, Marcelio A Shammami, Jada G Roberts, Amy Ralston

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Robin E KrugerCell and Molecular Biology Ph.D. Program, Michigan State University, East Lansing, MI, 48824, USA.
Tristan FrumDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
A Sophie BrummHuman Embryo and Stem Cell Laboratory, The Francis Crick Institute; London, NW1 1AT, UK.
Stephanie L HickeyResearch Technology Support Facility, Michigan State University, East Lansing, MI, 48824, USA.
Kathy K NiakanHuman Embryo and Stem Cell Laboratory, The Francis Crick Institute; London, NW1 1AT, UK.ORCID 0000-0003-1646-4734
Farina AzizCell and Molecular Biology Ph.D. Program, Michigan State University, East Lansing, MI, 48824, USA.
Marcelio A ShammamiReproductive and Developmental Sciences Training Program, Michigan State University, East Lansing, MI, 48824, USA.
Jada G RobertsMolecular, Cellular, and Integrative Physiology Ph.D. Program, Michigan State University, East Lansing, MI 48824, USA.
Amy RalstonReproductive and Developmental Sciences Training Program, Michigan State University, East Lansing, MI, 48824, USA.ORCID 0000-0003-3755-8262
Michigan State University · USBabraham Institute · GBThe Francis Crick Institute · GBUniversity of Michigan · US

Funding

Molecular mechanisms regulating formation of diverse stem cell progenitorsR35GM131759 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Amy Ralston · 2019 to 2026
$3.0M
Reproductive and Developmental Sciences Training Program - T32T32HD087166 · NICHD · MICHIGAN STATE UNIVERSITY · PI Ronald L Chandler, Keith E Latham · 2016 to 2026
$2.5M
NICHD NIH HHS T32 HD087166NIGMS NIH HHS R35 GM131759Wellcome Trust FC001120
6 · The paper itself

Abstract

Bone Morphogenic Protein (BMP) signaling plays an essential and highly conserved role in axial patterning in embryos of many externally developing animal species. However, in mammalian embryos, which develop inside the mother, early development includes an additional stage known as preimplantation. During preimplantation, the epiblast lineage is segregated from the extraembryonic lineages that enable implantation and development

Indexed as

epiblastextraembryonicmaternal and zygotic gene deletionmorphogenesispSMAD1/5/9

Identifiers

PMID38328075
PMCPMC10849569
OpenAlexW4391226573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.