Evidence map›Paper›PMID 38328068›Full record

ArticlebioRxiv : the preprint server for biology2024

Broadly inhibitory antibodies against severe malaria virulence proteins.

Raphael A Reyes, Sai Sundar Rajan Raghavan, Nicholas K Hurlburt, Viola Introini, Ikhlaq Hussain Kana, Rasmus W Jensen, Elizabeth Martinez-Scholze, Maria Gestal-Mato, Cristina Bancells Bau, Monica Lisa Fernández-Quintero and 15 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 7 institutions in 4 countries.

Raphael A ReyesDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0002-2234-4758
Sai Sundar Rajan RaghavanCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.ORCID 0000-0002-2575-2685
Nicholas K HurlburtVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.ORCID 0000-0001-9891-916X
Viola IntroiniEuropean Molecular Biology Laboratory (EMBL) Barcelona, Barcelona 08003, Spain.ORCID 0000-0001-9012-4696
Ikhlaq Hussain KanaCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.ORCID 0000-0003-1342-4737
Rasmus W JensenCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.
Elizabeth Martinez-ScholzeDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Maria Gestal-MatoEuropean Molecular Biology Laboratory (EMBL) Barcelona, Barcelona 08003, Spain.
Cristina Bancells BauEuropean Molecular Biology Laboratory (EMBL) Barcelona, Barcelona 08003, Spain.
Monica Lisa Fernández-QuinteroDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Johannes R LoefflerDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
James Alexander FergusonDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Wen-Hsin LeeDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0001-9445-6671
Greg Michael MartinDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Thor G TheanderCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.ORCID 0000-0002-3509-7514
Isaac SsewanyanaInfectious Disease Research Collaboration, Kampala, Uganda.ORCID 0000-0001-8605-2001
Margaret E FeeneyDepartment of Medicine, University of California San Francisco, San Francisco, CA 94110, USA.
Bryan GreenhouseDepartment of Medicine, University of California San Francisco, San Francisco, CA 94110, USA.
Sebastiaan BolDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0002-3843-6657
Andrew B WardDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0001-7153-3769
Maria BernabeuEuropean Molecular Biology Laboratory (EMBL) Barcelona, Barcelona 08003, Spain.ORCID 0000-0001-7212-6209
Marie PanceraVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Louise TurnerCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.
Evelien M BunnikDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0003-4003-3053
Thomas LavstsenCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Righospitalet, Copenhagen, Denmark.ORCID 0000-0002-3044-4249
Scripps Research Institute · USUniversity of Copenhagen · DKEuropean Molecular Biology Laboratory · ESThe University of Texas Health Science Center at San Antonio · USFred Hutch Cancer Center · USUniversity of California, San Francisco · USInfectious Diseases Research Collaboration · UG

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joaniter Immaculate Nankabirwa · 2010 to 2026
$29.3M
The role of γδ T cells in fetal and infant immune defense against malariaR01AI093615 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2011 to 2025
$9.1M
Computational models of naturally acquired immunity to falciparum malariaU01AI150741 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUTTE, ATUL J, GREENHOUSE, BRYAN R · 2020 to 2024
$7.4M
Defining conserved epitopes on polymorphic malaria antigensR01AI153425 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BUNNIK, EVELIEN MARGARETHA · 2021 to 2025
$2.7M
NRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8M
Mentoring translational scientists in international infectious disease researchK24AI144048 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bryan R Greenhouse · 2019 to 2026
$1.6M
Translational Studies of Plasmodium Falciparum Infection DynamicsK23AI076614 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENHOUSE, BRYAN R · 2008 to 2012
$609k
FACSAria Fusion cell sorter for Flow Cytometry Shared ResourceS10OD030432 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BERTON, MICHAEL T · 2022 to 2022
$596k
Molecular and cellular properties of broad and protective immune responses to the Plasmodium falciparum variant surface antigen responsible for severe malariaF31AI169993 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI REYES, RAPHAEL ANTHONY · 2022 to 2023
$46k
NCATS NIH HHS TL1 TR002647NCI NIH HHS P30 CA054174NIAID NIH HHS F31 AI169993NIAID NIH HHS K23 AI076614NIAID NIH HHS K24 AI144048NIAID NIH HHS R01 AI093615NIAID NIH HHS R01 AI153425NIAID NIH HHS U01 AI150741NIAID NIH HHS U19 AI089674NIH HHS S10 OD030432Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38328068
PMCPMC10849712
OpenAlexW4391261656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.