Evidence map›Paper›PMID 38328044›Full record

ArticlebioRxiv : the preprint server for biology2024

m6A-dependent circular RNA formation mediates tau-induced neurotoxicity.

Farzaneh Atrian, Paulino Ramirez, Jasmine De Mange, Marissa Marquez, Elias M Gonzalez, Miguel Minaya, Celeste M Karch, Bess Frost

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Farzaneh AtrianSam & Ann Barshop Institute for Longevity and Aging Studies, San Antonio, TX.
Paulino RamirezSam & Ann Barshop Institute for Longevity and Aging Studies, San Antonio, TX.ORCID 0000-0001-8532-9590
Jasmine De MangeSam & Ann Barshop Institute for Longevity and Aging Studies, San Antonio, TX.
Marissa MarquezSam & Ann Barshop Institute for Longevity and Aging Studies, San Antonio, TX.
Elias M GonzalezSam & Ann Barshop Institute for Longevity and Aging Studies, San Antonio, TX.
Miguel MinayaDepartment of Psychiatry, Washington University, St Louis, MO.ORCID 0000-0002-2573-6087
Celeste M KarchDepartment of Psychiatry, Washington University, St Louis, MO.ORCID 0000-0002-6854-5547
Bess FrostSam & Ann Barshop Institute for Longevity and Aging Studies, San Antonio, TX.ORCID 0000-0002-1212-8138
The University of Texas Health Science Center at San Antonio · USWashington University in St. Louis · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
TRAINING GRANT ON THE BIOLOGY OF AGINGT32AG021890 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Erzsebet Kokovay, JAMES FLOYD NELSON · 2003 to 2026
$11.4M
Mechanisms of tau- and aging-induced neurological dysfunction: Focus on the nucleusR01AG057896 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FROST, BESS · 2019 to 2023
$2.8M
Targeting Tau Proteoforms in Frontotemporal DementiaRF1NS110890 · NINDS · WASHINGTON UNIVERSITY · PI KARCH, CELESTE MARIE · 2021 to 2021
$1.8M
NIA NIH HHS R01 AG057896NIA NIH HHS T32 AG021890NIH HHS P40 OD018537NINDS NIH HHS RF1 NS110890
6 · The paper itself

Abstract

Circular RNAs (circRNAs), covalently closed RNA molecules that form due to back-splicing of RNA transcripts, have recently been implicated in Alzheimer's disease and related tauopathies. circRNAs are regulated by N

Indexed as

Alzheimer’s diseasecircRNAMblnucleusRNA methylationtauopathy

Identifiers

PMID38328044
PMCPMC10849734
OpenAlexW4391239563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.