Evidence map›Paper›PMID 38327922›Full record

ArticleCureus2024

Lupus-Induced Accelerated Heart Failure in a Young African American Female: Cardiovascular and Systemic Complications of Noncompliance to Maintenance Therapy and the Social Determinants of Cardiovascular Disease.

Ikpechukwu J Okorie, Edmund Appiah-Kubi, Philipa Owusu-Antwi, Evans Takyi, Derek Ugwendum, Annmarie Fernando, Muhammed Atere, Jay Nfonoyim

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ikpechukwu J OkorieInternal Medicine, Richmond University Medical Center, New York, USA.
Edmund Appiah-KubiInternal Medicine, Allegheny Health Network, Pittsburgh, USA.
Philipa Owusu-AntwiPsychiatry, Richmond University Medical Center, New York, USA.
Evans TakyiInternal Medicine, American University of Antigua, New York, USA.
Derek UgwendumInternal Medicine, Richmond University Medical Center, New York, USA.
Annmarie FernandoInternal Medicine, Richmond University Medical Center, New York, USA.
Muhammed AtereMedicine, Richmond University Medical Center, New York, USA.
Jay NfonoyimPulmonary and Critical Care, Richmond University Medical Center, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder characterized by dysregulations of the immune system with intermittent and remitting symptoms. SLE affects multiple organs and systems, including the cardiovascular system. This condition is associated with an increased risk of cardiovascular disease, particularly in younger patients. Our case report describes a patient who rapidly developed structural, functional, and electrophysiological cardiac abnormalities due to lupus-induced cardiomyopathy. The accelerating cardiac events were the result of medication noncompliance. Myocarditis and other potentially fatal cardiac complications associated with SLE have been the subject of numerous studies. This presentation appears to be the first to emphasize the rarity of lupus-induced cardiomyopathy, the importance of treatment adherence, the adverse cardiac effects of targeted therapeutic interventions, and the influence of social determinants of cardiovascular health on a patient's prognosis.

Indexed as

cardiomyopathyheart failurehydroxychloroquineleft ventricular hypertrophy (lvh)social determinants of health (sdoh)systemic lupus erythema

Identifiers

PMID38327922
PMCPMC10847065

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.