Evidence map›Paper›PMID 38327797›Full record

ArticleiScience2024

TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5.

Yuyuan Ge, Bin Jia, Peng Zhang, Baomin Chen, Liang Liu, Yan Shi, Shilu Huang, Xinglei Liu, Ran Wang, Yandong Xie and 2 more

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuyuan GeDepartment of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Bin JiaDepartment of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China.
Peng ZhangDepartment of Neurosurgery, People's Hospital of Rugao, Nantong 226500, China.
Baomin ChenDepartment of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Liang LiuDepartment of Neurosurgery, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing 210029, China.
Yan ShiDepartment of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Shilu HuangDepartment of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Xinglei LiuDepartment of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Ran WangDepartment of Neurosurgery, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing 210029, China.
Yandong XieDepartment of Neurosurgery, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing 210029, China.
Zhe LiDepartment of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China.
Jun DongDepartment of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-box transcription factor 15 (TBX15) plays important role in various cancers; however, its expression and role in glioma is still unclear. In this study, our findings indicated that TBX15 was increased in gliomas compared to normal brain tissues, and high levels of TBX15 were related to poor survival. Furthermore, TBX15 silencing in glioma cells not only inhibited their proliferation, migration, and invasion

Indexed as

CancerGeneticsMolecular biology

Identifiers

PMID38327797
PMCPMC10847739

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.