Evidence map›Paper›PMID 38327442›Full record

ArticleHeliyon2024

A scalable route to quaternary ammonium-functionalized AgCl colloidal antimicrobials inhibiting food pathogenic bacteria and biofilms.

Diellza Bajrami, Syed Imdadul Hossain, Alexia Barbarossa, Maria Chiara Sportelli, Rosaria Anna Picca, Luigi Gentile, Francesco Mastrolonardo, Antonio Rosato, Alessia Carocci, Nicola Antonio Colabufo and 2 more

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Diellza BajramiInstitute of Analytical and Bioanalytical Chemistry, Ulm University, Albert Einstein-Allee 11, 89081, Ulm, Germany.
Syed Imdadul HossainChemistry Department, University of Bari "Aldo Moro", Via E. Orabona, 4, 70126, Bari, Italy.
Alexia BarbarossaDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126, Bari, Italy.
Maria Chiara SportelliChemistry Department, University of Bari "Aldo Moro", Via E. Orabona, 4, 70126, Bari, Italy.
Rosaria Anna PiccaChemistry Department, University of Bari "Aldo Moro", Via E. Orabona, 4, 70126, Bari, Italy.
Luigi GentileChemistry Department, University of Bari "Aldo Moro", Via E. Orabona, 4, 70126, Bari, Italy.
Francesco MastrolonardoBiofordrug Srl, University of Bari "Aldo Moro", Via Dante 95, 70019, Triggiano, Bari, Italy.
Antonio RosatoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126, Bari, Italy.
Alessia CarocciDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126, Bari, Italy.
Nicola Antonio ColabufoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126, Bari, Italy.
Boris MizaikoffInstitute of Analytical and Bioanalytical Chemistry, Ulm University, Albert Einstein-Allee 11, 89081, Ulm, Germany.
Nicola CioffiChemistry Department, University of Bari "Aldo Moro", Via E. Orabona, 4, 70126, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores how a simple argentometric titration-like approach could be evolved into a versatile, scalable, fast, and robust strategy for the production of AgCl/quaternary ammonium compounds (QACs) colloidal nanoantimicrobials (NAMs). These systems, which are green, stable, cost-effective, and reproducible are found to be effective against a wide range of food pathogenic bacteria and biofilms. The option of a large-scale production for such colloidal suspensions was explored via the use of a peristaltic pump. The utilization of various types of biosafe QACs and a wide range of solvents including aqueous and organic ones renders this system green and versatile. Nanocolloids (NCs) were characterized using UV-Vis, X-ray photoelectron and Fourier transform infrared (FTIR) spectroscopies. Their morphology and crystalline nature were investigated by transmission electron microscopy (TEM) and selected area diffraction pattern (SAED). Nanoparticle (NP) size distribution and hydrodynamic radius were measured by dynamic light scattering (DLS), while the ζ-potential was found to be highly positive, thus indicating significant colloidal stability and antimicrobial activity. In fact, the higher the NP surface charge, the stronger was their bioactivity. Furthermore, the antibacterial and antibiofilm effects of the as-prepared NCs were tested against Gram-positive bacteria, such as

Indexed as

AgClAntibacterialAntibiofilmColloidsNanoantimicrobialsQACs

Identifiers

PMID38327442
PMCPMC10847915

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.